Characteristics and surgical treatment of recurrence melanoma of the foot: a case report and brief literature review.

European review for medical and pharmacological sciences 2022 Vol.26(8) p. 2918-2925

Liu XL, Li H, Wu GZ

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Abstract

[OBJECTIVE] Despite advances in plastic and reconstructive surgery, repairing soft tissue defects of the foot remains a complex surgical challenge when conventional methods cannot cover defects. We presented a case in which a free flap was used for reconstruction and reviewed the literature.

[PATIENTS AND METHODS] A 75-year-old woman with an acral melanoma history had a large exophytic mass on her right foot. Using PubMed, we found that reconstructive options in the literature include local flaps, fascial flaps, muscle flaps, and free flaps.

[RESULTS] Melanoma recurred four times at the same site after complete excision of the compound nevi in the present case. Melan A, Vimentin (+), S-100 (+), and HMB-45 positivity were found in immunohistochemical staining and increased Ki-67 proliferation. The defects in soft tissue are repaired using a free anterolateral thigh perforator flap. No complications were raised in the patient.

[CONCLUSIONS] Foot melanoma is difficult to be resected because it necessitates a wide excision, which can result in large defects. The free flap, in our experience, can easily be performed while preserving function and improving cosmesis. This flap is an appealing option for concealing defects in the distal extremities.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 free flap 피판재건술 dict 2
시술 flap 피판재건술 dict 2
해부 soft tissue scispacy 1
합병증 flaps scispacy 1
합병증 fascial flaps scispacy 1
합병증 muscle flaps scispacy 1
합병증 extremities scispacy 1
약물 [OBJECTIVE] scispacy 1
약물 [RESULTS] Melanoma scispacy 1
약물 [CONCLUSIONS] Foot melanoma scispacy 1
질환 melanoma C0025202
melanoma
scispacy 1
질환 acral melanoma C0346037
Acral Lentiginous Malignant Melanoma
scispacy 1
질환 exophytic scispacy 1
질환 nevi scispacy 1
기타 Vimentin scispacy 1
기타 S-100 scispacy 1
기타 HMB-45 scispacy 1
기타 Ki-67 scispacy 1
기타 anterolateral thigh perforator flap scispacy 1
기타 patient scispacy 1

MeSH Terms

Aged; Chronic Disease; Female; Humans; Melanoma; Perforator Flap; Plastic Surgery Procedures; Recurrence; Skin Neoplasms; Skin Transplantation; Soft Tissue Injuries; Thigh; Treatment Outcome; Cutaneous Malignant Melanoma

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