Pain management with popliteal block for fibular graft harvesting in head and neck reconstruction; a randomised double-blind placebo-controlled study.
Abstract
[BACKGROUND AND OBJECTIVES] Curative treatment for locally advanced head and neck tumours often includes reconstructive surgery using a microvascular free flap. Effective recuperation is essential but may be impeded by postoperative donor site pain. The aim of this study was to evaluate the effects of a continuous popliteal block on postoperative pain after fibular graft harvesting.
[MATERIAL AND METHODS] In this randomized double-blind placebo-controlled study adult patients scheduled for reconstructive head and neck surgery with a microvascular free fibular graft received an indwelling popliteal nerve block catheter and were randomized to receive continuous levobupivacaine/ropivacaine or placebo during the first postoperative week. Primary outcome was postoperative extremity pain assessed using the numerated rating scale (NRS). Secondary outcomes included opioid consumption.
[RESULTS] In total 24 patients were included. The median (median, IQR [range]) postoperative extremity NRS scores was lower in the local anaesthetic (LA) group (2, 0-3 [0-10]) compared to the placebo group (2, 1-4 [0-10]), p = 0.008. The LA group also experienced fewer episodes of breakthrough pain, defined as NRS ≥ 4 (17% vs 33% of observations), p = 0.009. Furthermore, median (median, IQR [range]) opioid consumption the first postoperative week was lower in the LA group (109 mg, 74-134 [19-611]) compared to the placebo group (202 mg, 135-241 [78-749]), p = 0.010. No complications attributed to the blocks were observed.
[CONCLUSION] Continuous popliteal block significantly reduced postoperative extremity pain and opioid consumption in patients undergoing fibular graft harvesting for head and neck reconstructive surgery.
[MATERIAL AND METHODS] In this randomized double-blind placebo-controlled study adult patients scheduled for reconstructive head and neck surgery with a microvascular free fibular graft received an indwelling popliteal nerve block catheter and were randomized to receive continuous levobupivacaine/ropivacaine or placebo during the first postoperative week. Primary outcome was postoperative extremity pain assessed using the numerated rating scale (NRS). Secondary outcomes included opioid consumption.
[RESULTS] In total 24 patients were included. The median (median, IQR [range]) postoperative extremity NRS scores was lower in the local anaesthetic (LA) group (2, 0-3 [0-10]) compared to the placebo group (2, 1-4 [0-10]), p = 0.008. The LA group also experienced fewer episodes of breakthrough pain, defined as NRS ≥ 4 (17% vs 33% of observations), p = 0.009. Furthermore, median (median, IQR [range]) opioid consumption the first postoperative week was lower in the LA group (109 mg, 74-134 [19-611]) compared to the placebo group (202 mg, 135-241 [78-749]), p = 0.010. No complications attributed to the blocks were observed.
[CONCLUSION] Continuous popliteal block significantly reduced postoperative extremity pain and opioid consumption in patients undergoing fibular graft harvesting for head and neck reconstructive surgery.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | microvascular
|
미세수술 | dict | 2 | |
| 시술 | free flap
|
피판재건술 | dict | 1 | |
| 해부 | fibular graft
|
scispacy | 1 | ||
| 합병증 | flap
|
scispacy | 1 | ||
| 약물 | levobupivacaine/ropivacaine
|
C0873118
levobupivacaine
|
scispacy | 1 | |
| 약물 | [BACKGROUND AND OBJECTIVES]
|
scispacy | 1 | ||
| 약물 | [MATERIAL AND
|
scispacy | 1 | ||
| 약물 | opioid
|
scispacy | 1 | ||
| 질환 | Pain
|
C0030193
Pain
|
scispacy | 1 | |
| 질환 | popliteal block
|
scispacy | 1 | ||
| 질환 | head and neck tumours
|
C0018671
Head and Neck Neoplasms
|
scispacy | 1 | |
| 질환 | postoperative pain
|
C0030201
Pain, Postoperative
|
scispacy | 1 | |
| 질환 | head and neck surgery
|
C1512343
Head and Neck Surgery
|
scispacy | 1 | |
| 질환 | postoperative extremity pain
|
scispacy | 1 | ||
| 질환 | NRS
→ numerated rating scale
|
scispacy | 1 | ||
| 질환 | significantly reduced postoperative extremity
|
scispacy | 1 | ||
| 질환 | head and neck reconstructive
|
scispacy | 1 | ||
| 질환 | head and neck
|
scispacy | 1 | ||
| 기타 | popliteal
|
scispacy | 1 | ||
| 기타 | patients
|
scispacy | 1 | ||
| 기타 | popliteal nerve
|
scispacy | 1 |
MeSH Terms
Adult; Analgesics, Opioid; Anesthetics, Local; Double-Blind Method; Humans; Pain Management; Pain Measurement; Postoperative Pain; Ropivacaine
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