Polymethylmethacrylate facial implant: a successful personal experience in Brazil for more than 9 years.
2/5 보강
🔎 핵심 키워드
필러 주입술 ×3
안면
감염
안면
facial wrinkles
Polymethylmethacrylate
Seventy-nine
microspheres
전체 NER ↓
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
환자: facial aging, facial atrophic scars, or lipoatrophy leading to facial defects
I · Intervention 중재 / 시술
injections of PMMA to correct facial defects
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
No late complications were observed. [CONCLUSION] PMMA used for the treatment of atrophy, depressions, and facial wrinkles has been shown to be effective, long lasting, safe, and gratifying to patients and physicians.
【연구 목적】 합성 영구 충전제인 폴리메틸메타크릴레이트(PMMA)가 노화, 위축성 흉터, 지방 위축으로 인한 안면 결손을 교정하는 데 있어 장기적인 효능과 안전성을 입증하기 위한 연구이다.
APA
Carvalho Costa IM, Salaro CP, Costa MC (2009). Polymethylmethacrylate facial implant: a successful personal experience in Brazil for more than 9 years.. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 35(8), 1221-7. https://doi.org/10.1111/j.1524-4725.2009.01216.x
MLA
Carvalho Costa IM, et al.. "Polymethylmethacrylate facial implant: a successful personal experience in Brazil for more than 9 years.." Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], vol. 35, no. 8, 2009, pp. 1221-7.
PMID
19438669 ↗
Abstract 한글 요약
[BACKGROUND] Synthetic permanent fillers for soft-tissue augmentation have acquired an important role in cosmetic improvement of patients with facial aging, facial atrophic scars, or lipoatrophy leading to facial defects. Polymethylmethacrylate (PMMA) is a filler introduced to the market as one option for long-lasting treatment. PMMA microspheres are purified, and the particles are larger than 20 microm. The product used as a filler has proven to be safe, effective, and long lasting.
[OBJECTIVE] To determine the efficacy and safety of PMMA as a facial filler.
[METHODS] Two hundred sixty-six patients (aged 17-72; 154 women) received injections of PMMA to correct facial defects. The number of sessions ranged from one to four, with an interval of 40 to 60 days between applications.
[RESULTS] Seventy-nine subjects (30%) had facial atrophy related to HIV infection, 159 (60%) had photoaging signs with deep wrinkles and atrophic areas, 25 (9%) had depressive scars from acne process, and three (1%) had residual depressions from lupus profundus. The results were satisfactory and long lasting. Side effects were transient. No late complications were observed.
[CONCLUSION] PMMA used for the treatment of atrophy, depressions, and facial wrinkles has been shown to be effective, long lasting, safe, and gratifying to patients and physicians.
[OBJECTIVE] To determine the efficacy and safety of PMMA as a facial filler.
[METHODS] Two hundred sixty-six patients (aged 17-72; 154 women) received injections of PMMA to correct facial defects. The number of sessions ranged from one to four, with an interval of 40 to 60 days between applications.
[RESULTS] Seventy-nine subjects (30%) had facial atrophy related to HIV infection, 159 (60%) had photoaging signs with deep wrinkles and atrophic areas, 25 (9%) had depressive scars from acne process, and three (1%) had residual depressions from lupus profundus. The results were satisfactory and long lasting. Side effects were transient. No late complications were observed.
[CONCLUSION] PMMA used for the treatment of atrophy, depressions, and facial wrinkles has been shown to be effective, long lasting, safe, and gratifying to patients and physicians.
【연구 목적】
합성 영구 충전제인 폴리메틸메타크릴레이트(PMMA)가 노화, 위축성 흉터, 지방 위축으로 인한 안면 결손을 교정하는 데 있어 장기적인 효능과 안전성을 입증하기 위한 연구이다.
【방법】
브라질에서 9년 이상 동안 수행된 개인 임상 경험을 바탕으로, 안면 결손 교정을 위해 PMMA 주사를 맞은 266명(17~72세, 여성 154명)을 대상으로 후향적 분석을 실시했다. 환자들은 40~60일 간격으로 1~4회에 걸쳐 주사를 맞았으며, 치료 결과와 부작용 발생 여부를 평가했다.
【주요 결과】
대상자 중 30%는 HIV 관련 안면 위축, 60%는 심한 주름과 위축을 동반한 광노화, 9%는 여드름 흉터, 1%는 루푸스 심부전증 잔여 함몰을 보였다. 치료 결과는 만족스럽고 장기적으로 유지되었으며, 부작용은 일시적이었고 후기 합병증은 관찰되지 않았다.
【임상적 시사점 (성형외과 의사 관점)】
PMMA는 비가역적 영구 충전제로, 악안면 재건이나 안면 윤곽 보정 시 장기적인 구조적 지지를 필요로 하는 환자에게 유용한 옵션이 될 수 있다. 다만, 미세구경 입자가 혈관 내로 유입될 경우 혈전색전증이나 조직 괴사 등 심각한 합병증을 유발할 수 있으므로, 정맥 및 동맥 주입을 피하기 위한 심층적인 안면 혈관 해부학적 이해가 필수적이다. 수술 전 환자 상담 시 영구적 부작용의 가능성과 이식 후 형성될 수 있는 섬유성 피막(fibrous capsule)으로 인한 결절 형성 가능성을 명확히 설명해야 한다. 특히 안면 신경 마비나 감염 이력이 있는 환자에서는 이식 부위의 혈류 공급과 면역 반응을 신중히 평가해야 한다. 장기적인 안전성 데이터는 긍정적이지만, 이식 부위의 물리적 특성 변화로 인해 향후 추가 수술이나 제거 시 기술적 어려움이 예상되므로, 다학제적 접근과 충분한 인내심을 가진 환자 선정이 중요하다.
추출된 의학 개체 (NER)
해부
안면 facial
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | filler
|
필러 주입술 | dict | 3 | |
| 해부 | facial
|
안면 | scispacy | 1 | |
| 합병증 | infection
|
감염 | dict | 1 | |
| 합병증 | facial
|
안면 | scispacy | 1 | |
| 합병증 | facial wrinkles
|
scispacy | 1 | ||
| 약물 | Polymethylmethacrylate
|
C0005533
Polymethyl Methacrylate
|
scispacy | 1 | |
| 약물 | Seventy-nine
|
C3828184
Seventy Nine
|
scispacy | 1 | |
| 약물 | microspheres
|
scispacy | 1 | ||
| 약물 | [RESULTS] Seventy-nine
|
scispacy | 1 | ||
| 질환 | atrophy
|
위축 |
C0333641
Atrophic
|
scispacy | 1 |
| 질환 | HIV infection
|
C0019693
HIV Infections
|
scispacy | 1 | |
| 질환 | depressive scars
|
scispacy | 1 | ||
| 질환 | acne
|
여드름 |
C0001144
Acne Vulgaris
|
scispacy | 1 |
| 질환 | lupus profundus
|
C0030327
Panniculitis, Lupus Erythematosus
|
scispacy | 1 | |
| 질환 | depressions
|
C0011570
Mental Depression
|
scispacy | 1 | |
| 질환 | wrinkles
|
주름 | scispacy | 1 | |
| 기타 | soft-tissue
|
연부조직 | scispacy | 1 | |
| 기타 | women
|
여성 | scispacy | 1 | |
| 기타 | HIV
|
scispacy | 1 |
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