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Preoperative scale proposal based on clinical outcome for elderly patients with ruptured intracranial aneurysms undergoing microsurgery.

The International journal of neuroscience 2023 Vol.133(10) p. 1204-1210

Aires R, Galafassi G, Pinho MCV, de Araújo Paz D, Salati T, Marchi C, de Aguiar PHP

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Abstract

[INTRODUCTION] Life expectancy in individuals has increased in recent years. There is no consensus in the literature on the best treatment for a ruptured aneurysm in the elderly (> 60 years), but some places only have microsurgery as a therapeutic strategy. This work aims to develop a prognostic scale for ruptured intracranial aneurysms in the elderly.

[MATERIAL AND METHODS] Two thousand five hundred thirty patients with subarachnoid hemorrhage were retrospectively evaluated in the last ten years, and 550 of them were elderly. We developed a prognostic scale from the analysis of medical records, clinical and tomographic features that had statistical significance. Glasgow Coma Outcome (GOS) was the outcome of interest and value < 0,05 was considered statistically significant.

[RESULTS] Five hundred fifty patients were evaluated, and the comorbidities that were independent variables for poor prognosis were smoking and arterial hypertension; clinical variables were Hunt-Hess, modified Rankin and Glasgow Coma Scale; tomographic was Fisher scale. Poor outcome was defined as GOS ≤ 3. Poor surgical outcomes were more remarkable in the high-risk factor categories, being 6.41 times higher among individuals who had 3 to 4 risk factors and 8.80 times higher among individuals with 5 to 6 risk factors.

[CONCLUSION] In some vascular neurosurgery services worldwide, microsurgery is the only therapeutic option. This scale aimed at the elderly patient individualizes the treatment and can predict the clinical outcome in ruptured intracranial aneurysms.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 microsurgery 미세수술 dict 3
합병증 intracranial scispacy 1
약물 smoking C0037369
Smoking
scispacy 1
약물 GOS ≤ C5420602
Genomics Outcome Scale
scispacy 1
약물 [MATERIAL AND scispacy 1
질환 ruptured intracranial aneurysms scispacy 1
질환 ruptured aneurysm C0162869
Aneurysm, Ruptured
scispacy 1
질환 intracranial aneurysms C0007766
Intracranial Aneurysm
scispacy 1
질환 subarachnoid hemorrhage C0038525
Subarachnoid Hemorrhage
scispacy 1
질환 Coma C0009421
Comatose
scispacy 1
질환 hypertension C0020538
Hypertensive disease
scispacy 1
기타 arterial scispacy 1
기타 vascular scispacy 1

MeSH Terms

Humans; Aged; Intracranial Aneurysm; Retrospective Studies; Microsurgery; Treatment Outcome; Subarachnoid Hemorrhage; Aneurysm, Ruptured

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