Intraoperative argatroban vessel irrigation during microsurgical anastomosis in heparin-induced thrombocytopenia patients: About two cases.
Abstract
Patients with heparin-induced thrombocytopenia or confirmed allergies to heparin have a contraindication to heparin therapy, which poses a problem for intraoperative free flap irrigation in reconstruction. The use of argatroban as an alternative to heparin allowed us to perform a free flap for leg salvage and a deep inferior epigastric perforator flap for breast reconstruction without microvascular complication, with a 0.01 mg/mL solution. We reported two cases of using an alternative treatment to heparin in an emergency and planned surgeries for vessel irrigation during microsurgical anastomosis reconstruction without microvascular complications, suggesting the reliability and effectiveness of its use in case of contraindication to heparin.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | free flap
|
피판재건술 | dict | 2 | |
| 시술 | microvascular
|
미세수술 | dict | 2 | |
| 시술 | flap
|
피판재건술 | dict | 1 | |
| 해부 | breast
|
유방 | dict | 1 | |
| 해부 | leg
|
scispacy | 1 | ||
| 약물 | argatroban
|
C0048470
argatroban
|
scispacy | 1 | |
| 약물 | heparin
|
C0019134
heparin
|
scispacy | 1 | |
| 약물 | argatroban vessel
|
scispacy | 1 | ||
| 질환 | heparin-induced thrombocytopenia
|
C0272285
Heparin-induced thrombocytopenia
|
scispacy | 1 | |
| 질환 | allergies
|
C0020517
Hypersensitivity
|
scispacy | 1 | |
| 기타 | patients
|
scispacy | 1 | ||
| 기타 | vessel
|
scispacy | 1 |
MeSH Terms
Humans; Reproducibility of Results; Heparin; Mammaplasty; Thrombocytopenia; Anastomosis, Surgical; Microsurgery; Perforator Flap; Arginine; Pipecolic Acids; Sulfonamides
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