[Indocyanine green is an integral part of breast reconstructive surgery using perforator flaps].
Abstract
[INTRODUCTION] The use of allotransplants for breast reconstruction in surgical stage of the the breast cancer treatment requires tissue perfusion control. The aim of the study was to analyze the effectiveness of using indocyanine green as a drug for determining the perfusion of perforant flaps in breast reconstructive surgery.
[MATERIAL AND METHODS] A retrospective series of observations of 27 breast reconstructions using autologous transplants is presented: 19 reconstructions with DIEP-flap, 2 with SIEA-flap, 5 with TD-flap; 1 with thoracoepigastric flap. Intraoperative fluorescence angiography was performed using a Stryker device (5900 Optical Court, USA). The intensity of the flap fluorescence was recorded after intravenous bolus injection of 7.5 mg indocyanine green.
[RESULTS AND DISCUSSION] The optimal time interval from the moment of drug administration to indicative visualization of flap perfusion was 55-60 seconds. In all patients, the area of insufficient blood flow was excised within intensively blood-supplied tissues, according to mapping data with the indocyanine green. With free transplant of flaps postoperative complications during follow-up were recorded in 1 (4.8%) case (marginal necrosis), which is associated with insufficient compression of auxiliary vessels (violation of the dominant vessel contrast technique). With non-free transplant of flaps no complications were detected in the postoperative period.
[CONCLUSIONS] Indocyanine green allows to prevent necrotic changes and reduce the rehabilitation period. The optimal time for the indicative visualization of flap perfusion was 55-60 seconds. The use of indocyanine green in free transplant of flaps ensured a postoperative period without complications in 20 (95.2%) cases, in non-free flap transplantation - in 6 (100%) cases.
[MATERIAL AND METHODS] A retrospective series of observations of 27 breast reconstructions using autologous transplants is presented: 19 reconstructions with DIEP-flap, 2 with SIEA-flap, 5 with TD-flap; 1 with thoracoepigastric flap. Intraoperative fluorescence angiography was performed using a Stryker device (5900 Optical Court, USA). The intensity of the flap fluorescence was recorded after intravenous bolus injection of 7.5 mg indocyanine green.
[RESULTS AND DISCUSSION] The optimal time interval from the moment of drug administration to indicative visualization of flap perfusion was 55-60 seconds. In all patients, the area of insufficient blood flow was excised within intensively blood-supplied tissues, according to mapping data with the indocyanine green. With free transplant of flaps postoperative complications during follow-up were recorded in 1 (4.8%) case (marginal necrosis), which is associated with insufficient compression of auxiliary vessels (violation of the dominant vessel contrast technique). With non-free transplant of flaps no complications were detected in the postoperative period.
[CONCLUSIONS] Indocyanine green allows to prevent necrotic changes and reduce the rehabilitation period. The optimal time for the indicative visualization of flap perfusion was 55-60 seconds. The use of indocyanine green in free transplant of flaps ensured a postoperative period without complications in 20 (95.2%) cases, in non-free flap transplantation - in 6 (100%) cases.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | flap
|
피판재건술 | dict | 7 | |
| 해부 | breast
|
유방 | dict | 5 | |
| 시술 | free flap
|
피판재건술 | dict | 1 | |
| 해부 | allotransplants
|
scispacy | 1 | ||
| 해부 | tissue
|
scispacy | 1 | ||
| 해부 | DIEP-flap
|
scispacy | 1 | ||
| 해부 | intravenous
|
scispacy | 1 | ||
| 해부 | blood
|
scispacy | 1 | ||
| 해부 | blood-supplied tissues
|
scispacy | 1 | ||
| 합병증 | necrosis
|
괴사 | dict | 1 | |
| 합병증 | perforator flaps
|
scispacy | 1 | ||
| 합병증 | thoracoepigastric flap
|
scispacy | 1 | ||
| 합병증 | flaps
|
scispacy | 1 | ||
| 약물 | Indocyanine green
|
C0021234
indocyanine green
|
scispacy | 1 | |
| 약물 | [INTRODUCTION]
|
scispacy | 1 | ||
| 약물 | [MATERIAL AND METHODS] A
|
scispacy | 1 | ||
| 약물 | [RESULTS AND
|
scispacy | 1 | ||
| 약물 | non-free
|
scispacy | 1 | ||
| 약물 | [CONCLUSIONS] Indocyanine
|
scispacy | 1 | ||
| 질환 | breast cancer
|
C0006142
Malignant neoplasm of breast
|
scispacy | 1 | |
| 질환 | necrotic
|
C0027540
Necrosis
|
scispacy | 1 | |
| 기타 | 55-60
|
scispacy | 1 | ||
| 기타 | patients
|
scispacy | 1 | ||
| 기타 | vessels
→ vessel contrast technique
|
scispacy | 1 | ||
| 기타 | vessel
|
scispacy | 1 |
MeSH Terms
Humans; Indocyanine Green; Female; Mammaplasty; Perforator Flap; Middle Aged; Breast Neoplasms; Retrospective Studies; Adult; Fluorescein Angiography; Postoperative Complications; Coloring Agents; Mastectomy
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