Use of the Superior Thyroid Artery as a Recipient Artery in Head and Neck Free Flap Reconstruction: Effects on Post-Operative Hypothyroidism.
Abstract
[BACKGROUND] The superior thyroid artery (STA) as a recipient vessel in free flap reconstruction may theoretically impact thyroid function. This study aimed to assess whether the use of the STA has an adverse effect on thyroid function.
[METHODS] Retrospective review of 101 head and neck reconstructive cases. Thyroid function tests were reviewed within 1 year of surgery.
[RESULTS] The STA was used in 40 cases. The STA cohort had significantly higher TSH levels than the non-STA cohort (7.34 v. 2.87 mU/L, p = 0.02). About 27.5% developed subclinical post-operative hypothyroidism and 17.5% required new levothyroxine supplementation in the STA group.
[CONCLUSION] This represents the first study to our knowledge assessing the impact of the STA as a recipient vessel on postoperative thyroid function. While we found a statistically significant difference in average TSH after using the STA, the average TSH/FT4 values were subclinical. Post-operative monitoring for hypothyroidism is warranted in this population.
[METHODS] Retrospective review of 101 head and neck reconstructive cases. Thyroid function tests were reviewed within 1 year of surgery.
[RESULTS] The STA was used in 40 cases. The STA cohort had significantly higher TSH levels than the non-STA cohort (7.34 v. 2.87 mU/L, p = 0.02). About 27.5% developed subclinical post-operative hypothyroidism and 17.5% required new levothyroxine supplementation in the STA group.
[CONCLUSION] This represents the first study to our knowledge assessing the impact of the STA as a recipient vessel on postoperative thyroid function. While we found a statistically significant difference in average TSH after using the STA, the average TSH/FT4 values were subclinical. Post-operative monitoring for hypothyroidism is warranted in this population.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | free flap
|
피판재건술 | dict | 2 | |
| 해부 | Thyroid
|
scispacy | 1 | ||
| 해부 | flap
|
scispacy | 1 | ||
| 약물 | levothyroxine
|
C0040165
levothyroxine
|
scispacy | 1 | |
| 약물 | TSH/FT4
|
scispacy | 1 | ||
| 약물 | [BACKGROUND]
|
scispacy | 1 | ||
| 질환 | Hypothyroidism
|
C0020676
Hypothyroidism
|
scispacy | 1 | |
| 질환 | head and neck reconstructive
|
scispacy | 1 | ||
| 질환 | Head and Neck Free Flap
|
scispacy | 1 | ||
| 질환 | STA
→ superior thyroid artery
|
scispacy | 1 | ||
| 질환 | head and neck
|
scispacy | 1 | ||
| 기타 | thyroid artery
|
scispacy | 1 | ||
| 기타 | STA
→ superior thyroid artery
|
scispacy | 1 | ||
| 기타 | vessel
|
scispacy | 1 | ||
| 기타 | TSH
|
scispacy | 1 |
MeSH Terms
Humans; Hypothyroidism; Retrospective Studies; Male; Female; Middle Aged; Free Tissue Flaps; Plastic Surgery Procedures; Thyroid Gland; Aged; Head and Neck Neoplasms; Adult; Postoperative Complications; Thyroid Function Tests; Arteries; Thyrotropin; Thyroxine
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