Effect of Enhanced Recovery after Surgery in Morbidly Obese Patients Undergoing Free Flap Breast Reconstruction.

Journal of reconstructive microsurgery 2025 Vol.41(9) p. 733-740

Stephens KL, DeVito RG, Hollenbeck ST, Campbell CA, Stranix JT

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Abstract

Enhanced recovery after surgery (ERAS) pathways have been widely implemented across many surgical practices, including autologous breast reconstruction. However, the benefits of ERAS in the morbidly obese population have yet to be defined.A retrospective chart review of patients undergoing deep inferior epigastric artery perforator (DIEP) flap breast reconstruction at our institution from 2017 to 2022 was performed. Length of stay (LOS), intensive care unit (ICU) utilization, opioid usage, cost, and flap outcomes were analyzed in patients with body mass index greater than 35 before and after ERAS implementation.Thirty-five morbidly obese patients receiving DIEP flap breast reconstruction were identified before ERAS and 18 after ERAS. There were no differences in unilateral versus bilateral or immediate versus delayed reconstruction. LOS decreased with ERAS (3.43 vs. 2.06 days,  < 0.0000001). ICU utilization decreased with ERAS (0.94 vs. 0.0 days,  < 0.0001). Daily and total opioid usage decreased with ERAS (41.8 vs. 17.9 morphine milligram equivalent [MME],  < 0.0001; 190.5 vs. 54.7 MME,  < 0.0001). Financial metrics improved with ERAS, including decreased total cost ($33,454 vs. $25,079,  = 0.0002) and increased cost margin ($4,458 vs. -$8,306,  = 0.004). There were no differences in donor or recipient site outcomes including flap loss, deep venous thrombosis/pulmonary embolism, hernia/bulge, delayed wound healing, revisions, and blood loss.ERAS pathways maintain benefits in the morbidly obese population undergoing abdominally based autologous breast reconstruction, including decreased LOS, ICU utilization, opioid use, and cost while maintaining successful reconstruction outcomes.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 breast 유방 dict 5
시술 flap 피판재건술 dict 3
시술 free flap 피판재건술 dict 1
시술 diep flap 피판재건술 dict 1
해부 blood scispacy 1
합병증 Flap Breast scispacy 1
합병증 wound scispacy 1
약물 morphine C0026549
morphine
scispacy 1
약물 MME C0066662
1,2,3,4,9,9-hexachloro-1,4,4a,5,8,8a-hexahydro-6- methyl-6,7-epoxy-1,4-methanonaphthalene
scispacy 1
약물 opioid scispacy 1
질환 DIEP → deep inferior epigastric artery perforator scispacy 1
질환 obese C0028754
Obesity
scispacy 1
질환 DIEP flap breast reconstruction scispacy 1
질환 venous thrombosis/pulmonary embolism scispacy 1
질환 hernia/bulge scispacy 1
질환 blood loss C0019080
Hemorrhage
scispacy 1
질환 LOS → Length of stay scispacy 1
기타 Patients scispacy 1
기타 DIEP flap breast scispacy 1
기타 MME scispacy 1
기타 LOS → Length of stay scispacy 1

MeSH Terms

Humans; Mammaplasty; Obesity, Morbid; Female; Retrospective Studies; Middle Aged; Length of Stay; Enhanced Recovery After Surgery; Free Tissue Flaps; Perforator Flap; Adult; Treatment Outcome; Epigastric Arteries; Breast Neoplasms

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