Distal Flap Heparinisation Versus Systemic Bolus of Low Molecular Weight Heparin for the Prevention of Vascular Congestion in Microvascular Free Flaps: A Randomised Clinical Trial.
2/5 보강
TL;DR
It was concluded that distal heparinisation during microvascular anastomosis is better than systemic heparin and local irrigation in preventing the formation of thrombus.
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
30 patients who underwent free flap surgeries which were divided into three groups of 10 each.
I · Intervention 중재 / 시술
free flap surgeries which were divided into three groups of 10 each
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
추출되지 않음
OpenAlex 토픽 ·
Reconstructive Surgery and Microvascular Techniques
Hemostasis and retained surgical items
Trauma Management and Diagnosis
It was concluded that distal heparinisation during microvascular anastomosis is better than systemic heparin and local irrigation in preventing the formation of thrombus.
APA
Srinidhi Kasthurirengan, Mariappan Murugan, et al. (2026). Distal Flap Heparinisation Versus Systemic Bolus of Low Molecular Weight Heparin for the Prevention of Vascular Congestion in Microvascular Free Flaps: A Randomised Clinical Trial.. Journal of maxillofacial and oral surgery, 25(1), 14-18. https://doi.org/10.1007/s12663-023-01999-0
MLA
Srinidhi Kasthurirengan, et al.. "Distal Flap Heparinisation Versus Systemic Bolus of Low Molecular Weight Heparin for the Prevention of Vascular Congestion in Microvascular Free Flaps: A Randomised Clinical Trial.." Journal of maxillofacial and oral surgery, vol. 25, no. 1, 2026, pp. 14-18.
PMID
41648692 ↗
Abstract 한글 요약
[AIM] The aim of the study is to compare the efficacy of distal flap heparinisation and intravenous bolus of low molecular weight heparin for the prevention of vascular congestion in microvascular free flaps.
[INTRODUCTION] Microvascular free flap surgeries are prone to various complications that can lead to flap failure. Among the various complications, thrombus formation is one of the most common complications leading to flap failure. Various methods can be used to prevent vascular congestion which include preoperative multiagent regimen, intraoperative distal heparinisation, systemic heparin bolus and postoperative use of drugs such as aspirin, dextran, low molecular weight heparin, etc. In this study, we compare three groups, i.e. systemic bolus of heparin, distal heparinisation and local irrigation using heparinised saline.
[MATERIALS AND METHODS] The present study included 30 patients who underwent free flap surgeries which were divided into three groups of 10 each. Group 1 included patients who underwent free flap surgery and were given intravenous bolus of low molecular weight heparin (LMWH), Group 2 included patients who underwent free flap surgery without intravenous bolus of LMWH but distal flap heparinisation was done where heparin was injected in the harvested artery and Group 3 included patients who underwent free flap surgery with only local irrigation of heparinised saline during microvascular anastomosis.
[RESULTS] It was found that the percentage of patients who tested positive was 10% and 20% for intraoperative and postoperative for Group 1 which is the highest while Group 2 has no patients who tested positive for the formation of thrombus. Group 3-only local irrigation has only 20% positive in the postoperative tests while no positive milking or expansile test intraoperatively, we can observe that distal heparinisation is the best method as it has literally no patients with both intra- and postoperative formations of vascular congestion when compared to systemic administration of heparin and local irrigation using heparinised saline.
[CONCLUSION] It was concluded that distal heparinisation during microvascular anastomosis is better than systemic heparin and local irrigation in preventing the formation of thrombus.
[INTRODUCTION] Microvascular free flap surgeries are prone to various complications that can lead to flap failure. Among the various complications, thrombus formation is one of the most common complications leading to flap failure. Various methods can be used to prevent vascular congestion which include preoperative multiagent regimen, intraoperative distal heparinisation, systemic heparin bolus and postoperative use of drugs such as aspirin, dextran, low molecular weight heparin, etc. In this study, we compare three groups, i.e. systemic bolus of heparin, distal heparinisation and local irrigation using heparinised saline.
[MATERIALS AND METHODS] The present study included 30 patients who underwent free flap surgeries which were divided into three groups of 10 each. Group 1 included patients who underwent free flap surgery and were given intravenous bolus of low molecular weight heparin (LMWH), Group 2 included patients who underwent free flap surgery without intravenous bolus of LMWH but distal flap heparinisation was done where heparin was injected in the harvested artery and Group 3 included patients who underwent free flap surgery with only local irrigation of heparinised saline during microvascular anastomosis.
[RESULTS] It was found that the percentage of patients who tested positive was 10% and 20% for intraoperative and postoperative for Group 1 which is the highest while Group 2 has no patients who tested positive for the formation of thrombus. Group 3-only local irrigation has only 20% positive in the postoperative tests while no positive milking or expansile test intraoperatively, we can observe that distal heparinisation is the best method as it has literally no patients with both intra- and postoperative formations of vascular congestion when compared to systemic administration of heparin and local irrigation using heparinised saline.
[CONCLUSION] It was concluded that distal heparinisation during microvascular anastomosis is better than systemic heparin and local irrigation in preventing the formation of thrombus.
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | microvascular
|
미세수술 | dict | 5 | |
| 시술 | free flap
|
피판재건술 | dict | 5 | |
| 시술 | flap
|
피판재건술 | dict | 5 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
함께 등장하는 도메인
이 논문이 속한 카테고리와 같은 논문에서 자주 함께 다뤄지는 카테고리들
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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