Adverse reactions to dermal fillers: a review of European experiences.
Abstract
[BACKGROUND] In Europe, numerous dermal fillers have been utilized for the past decade. A lot of drawbacks have been reported and sometimes, severe complications occurred.
[OBJECTIVE] Our purpose is to report the clinical aspects of the adverse reactions following injections of some of the dermal fillers. Histological aspects of complications are also described.
[RESULTS] Adverse reactions secondary to biodegradable products are usually time limited, but with the non-biodegradable products, we have observed severe, persistent, and recurrent complications. Histological examinations, in cases of non-biodegradable products, may show the presence and persistence of the filler.
[CONCLUSION] For the moment, there is no ideal dermal filler. All fillers can lead to adverse events and we need to inform patients fully before injecting. Clinical studies with long-term follow-up before launching a new product on the market are recommended. We believe that in Europe, at present, the CE mark is not a guarantee of safety of dermal fillers.
[OBJECTIVE] Our purpose is to report the clinical aspects of the adverse reactions following injections of some of the dermal fillers. Histological aspects of complications are also described.
[RESULTS] Adverse reactions secondary to biodegradable products are usually time limited, but with the non-biodegradable products, we have observed severe, persistent, and recurrent complications. Histological examinations, in cases of non-biodegradable products, may show the presence and persistence of the filler.
[CONCLUSION] For the moment, there is no ideal dermal filler. All fillers can lead to adverse events and we need to inform patients fully before injecting. Clinical studies with long-term follow-up before launching a new product on the market are recommended. We believe that in Europe, at present, the CE mark is not a guarantee of safety of dermal fillers.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | filler
|
필러 주입술 | dict | 1 | |
| 시술 | dermal filler
|
필러 주입술 | dict | 1 |
MeSH Terms
Acrylates; Acrylic Resins; Biocompatible Materials; Cellulose; Collagen; Cosmetic Techniques; Drug Eruptions; Granuloma, Foreign-Body; Humans; Hyaluronic Acid; Hydrogels; Injections, Intradermal; Lactic Acid; Mannitol; Polyethylenes; Polymers; Polymethyl Methacrylate; Polypropylenes; Silicones; Polyacrylamides
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