Focal Dystonia in Hemiplegic Upper Limb: Favorable Effect of Cervical Microsurgical DREZotomy Involving the Ventral Horn - A Report of 3 Patients.

Stereotactic and functional neurosurgery 2016 Vol.94(3) p. 140-6

Sindou M, Georgoulis G

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Abstract

[BACKGROUND] Focal dystonia in hemiplegic upper limbs is poorly responsive to medications or classical neurosurgical treatments. Only repeated botulinum toxin injections show efficacy, but in most severe cases effects are transient.

[OBJECTIVES] Cervical DREZ lesioning, which has proven efficacious in hyperspasticity when done deeply (3-5 mm) in the dorsal horn, may have favorable effects on the dystonic component when performed down to, and including, the base of the ventral horn (5-6 mm in depth).

[METHODS] Three patients underwent deep cervical microsurgical DREZotomy (MDT) for focal dystonia in the upper limb.

[RESULTS] Hypertonia was reduced, and sustained dystonic postures were suppressed. Residual motor function (hidden behind hypertonia) came to the surface.

[CONCLUSIONS] Cervical MDT may be a useful armamentarium for treating refractory focal dystonia in the upper limb.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 1

MeSH Terms

Adult; Brain Diseases; Brain Injuries; Cervical Vertebrae; Dystonic Disorders; Electrocoagulation; Hemiplegia; Humans; Male; Microsurgery; Muscle Spasticity; Quadriplegia; Spinal Cord Ventral Horn; Upper Extremity; Young Adult

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