Intrasphincteric Botulinum Toxin Injections to Treat Achalasia Diagnosed in 615 Pregnancy: A Case Report.

The Journal of reproductive medicine 2016 Vol.61(11-12) p. 615-7

Holliday N, Baker S

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Abstract

[BACKGROUND] Achalasia is an esophageal smooth muscle disorder characterized by failure of the lower esophageal sphincter to relax with swallowing.

[CASE] A 17-year-old primigravid woman with an intrauterine pregnancy at 31+3 weeks reported an unintentional 22.5 kg weight loss in 2 years. Her body mass index was 15.9. Her symptoms included nausea, regurgitation, and worsening dysphagia. MRI suggested achalasia. She was started on total parenteral nutrition until she developed bacteremia. An esophagogastroduodenoscopy with Duotube placement and botulinum toxin A injections were performed. Tube feeds were initiated and continued until the Duotube became obstructed. The patient delivered at 37+4 weeks with mild preeclampsia. A postpartum barium swallow test indicated achalasia.

[CONCLUSION] A history of dysphagia to solids and/or liquids with weight loss should raise clinical suspicions for achalasia.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 2

MeSH Terms

Adolescent; Botulinum Toxins, Type A; Esophageal Achalasia; Female; Gravidity; Humans; Neuromuscular Agents; Pregnancy; Pregnancy Complications; Treatment Outcome

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