Botulinum Toxin: Techniques Within Pediatric Physiatry.

PM & R : the journal of injury, function, and rehabilitation 2019 Vol.11(1) p. 38-44

Paulson A, Zigler CK, Houtrow A, Pruitt D

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Abstract

[BACKGROUND] Intramuscular botulinum toxin injections are used for treatment of focal spasticity in children, particularly in those with a diagnosis of cerebral palsy. There are a variety of techniques used when performing botulinum toxin injections without clear standards for pediatric providers.

[OBJECTIVE] To describe current practice techniques for botulinum toxin injections among pediatric physiatrists.

[DESIGN] Cross-sectional survey using RedCap Software.

[SETTING] Pediatric physiatrists who perform botulinum toxin injections.

[PARTICIPANTS] Survey of 307 pediatric physiatrists.

[METHODS] Analysis of data from the 2017 practice survey of pediatric physiatrists in the United States.

[MAIN OUTCOME MEASUREMENTS] Physicians were asked the primary botulinum toxin used, common dosing information, the role of localization, and the role of sedation and distraction in their practice.

[RESULTS] Nearly all pediatric physiatrists use OnabotulinumtoxinA as the primary formulation of botulinum toxin. The maximum dose per body weight used per injection series had a median of 15 units/kilogram and a median maximum total dose of 500 units. Sixty-five percent of pediatric physiatrists report using sedation, of any type, for botulinum toxin injections. When using sedation, the most common primary method was general anesthesia (38.9%), followed by enteral or nasal anxiolytic with the patient awake (26.2%). The most common reported intended injection site for botulinum toxin was "in multiple sites spread throughout the muscle" (67.9%), and then "one site of the muscle at the motor point" (17.1%). Large muscles were injected using primarily anatomic guidance (75.6%) and electromyography (50.8%), and small muscles were primarily completed with electromyography (73.6%) and anatomic guidance (49.2%).

[CONCLUSION] There is considerable variability present in one common procedure performed by pediatric physiatrists.

[LEVEL OF EVIDENCE] NA.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 9

MeSH Terms

Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Electromyography; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Injections, Intramuscular; Male; Muscle Spasticity; Neuromuscular Agents; Pediatrics; Physiatrists; Practice Patterns, Physicians'; Surveys and Questionnaires; Treatment Outcome; United States

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