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Osteoarthritis of the hip conservative treatment with type A botulinum toxin.

Gaceta medica de Mexico 2019 Vol.155(Suppl 1) p. S44-S48

Durán-Hernández S, Soto-Rodríguez JF, Allen-Bobadilla J, Durán-Hernández N, García-Mosco P

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[INTRODUCTION] Osteoarthritis (OA) of the hip is a low-grade inflammatory disease of multiple etiology that has a limited conservative management and insufficiently explored.

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  • p-value p < 0.0001
  • p-value p < 0.002

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BibTeX ↓ RIS ↓
APA Durán-Hernández S, Soto-Rodríguez JF, et al. (2019). Osteoarthritis of the hip conservative treatment with type A botulinum toxin.. Gaceta medica de Mexico, 155(Suppl 1), S44-S48. https://doi.org/10.24875/GMM.M19000289
MLA Durán-Hernández S, et al.. "Osteoarthritis of the hip conservative treatment with type A botulinum toxin.." Gaceta medica de Mexico, vol. 155, no. Suppl 1, 2019, pp. S44-S48.
PMID 31638614

Abstract

[INTRODUCTION] Osteoarthritis (OA) of the hip is a low-grade inflammatory disease of multiple etiology that has a limited conservative management and insufficiently explored. The application of botulinum toxin type A (BoNT-A) produces in the applied muscle a temporary, delimitable and reversible flaccid paralysis, which applied in a strategic way achieves to reduce mechanical stress and pain.

[OBJECTIVE] To evaluate the effect on pain perception, functionality and rigidity and changes in flexibility, internal and external rotation, before and 90 days after the application of BoNT-A.

[METHODS] Clinical, experimental, longitudinal, open study, with a total of 35 patients and 45 hips treated. BoNT-A of 500 U was applied in iliac, adductor brevis and longus muscles.

[RESULTS] The Wilcoxon test was used to compare the evaluation scores on days 0-90, observing the decrease in referred pain (p < 0.0001), rigidity (p < 0.002), improved perceived function (p < 0.001) and mobility arcs: flexion, internal and external rotation (p < 0.0001).

[CONCLUSIONS] The treatment with BoNT-A provides a conservative and safe option for the management of symptoms and physical restraint caused by hip OA.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 2

MeSH Terms

Adult; Aged; Aged, 80 and over; Botulinum Toxins, Type A; Conservative Treatment; Female; Humans; Injections, Intramuscular; Longitudinal Studies; Male; Middle Aged; Neuromuscular Agents; Osteoarthritis, Hip; Statistics, Nonparametric

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