Assessing the utility of non-surgical treatments in the management of vocal process granulomas.

The Journal of laryngology and otology 2020 Vol.134(1) p. 68-73

Rudman JR, McGee CS, Diaz J, Rosow DE

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Abstract

[OBJECTIVE] To determine whether patients would have equivalent or improved outcomes when receiving non-surgical management versus surgical removal for vocal process granulomas.

[METHODS] A chart review was performed for 53 adults with vocal process granulomas. All patients received baseline anti-reflux treatment consisting of twice-daily proton pump inhibitors and vocal hygiene education. Further treatment approaches were divided into non-surgical (i.e. inhaled corticosteroids, voice therapy, botulinum toxin injections) and surgical groups. Subjective parameters (Voice Handicap Index 10 and Reflux Symptom Index) and outcomes were tabulated and statistically compared. Cause of granuloma was also analysed to determine if this influenced outcomes.

[RESULTS] Of 53 patients, 47 (89 per cent) experienced reduction in granuloma size, while 37 (70 per cent) experienced complete resolution. The rate of complete granuloma resolution after initial treatment strategy alone was significantly higher in non-surgical compared to surgical patients (67 and 30 per cent, respectively; p = 0.039). No difference in outcome was seen between iatrogenic and idiopathic granulomas.

[CONCLUSION] Non-surgical patients were more likely to experience initial treatment success than those who underwent surgical removal. Continued emphasis should be placed on conservative treatment options prior to surgery for patients with this condition.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 1

MeSH Terms

Adult; Aged; Combined Modality Therapy; Disease Management; Female; Granuloma; Humans; Laryngitis; Male; Middle Aged; Otorhinolaryngologic Surgical Procedures; Proton Pump Inhibitors; Treatment Outcome; Vocal Cords; Voice Quality; Voice Training

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