A mini review on the common methods of pain reduction before filler and botulinum toxin injection.

[BACKGROUND] As the desire for beauty and youthful appearance has increased in recent years, cosmetic injections are getting more attention. However, patients discomfort during these injections is a challenging issue.

[AIM] This review explores common approaches to reduce pain and discomfort during cosmetic injections through the available literature.

[METHODS] The eligible studies through searching in PubMed have been entered to evaluate the common methods of pain reduction for cosmetic injections.

[RESULTS] According to reviewed studies, vibration, local anesthesia, and vapocoolant anesthesia are common methods applied in order to reduce pain and discomfort in patients. All of these methods are able to reduce pain through their affects on neuron fibers.

[CONCLUSION] It seems that all common approaches can result in some amount of pain reduction. Using a combination of these methods during injections, practitioners can successfully reduce the pain of injection.