Botulinum toxin: Pharmacology and injectable administration for the treatment of primary hyperhidrosis.
Abstract
Hyperhidrosis is a dermatological condition defined by excessive sweating beyond thermoregulatory needs with significant effects on patients' quality of life. Hyperhidrosis is categorized as primary or secondary: primary hyperhidrosis is mostly focal and idiopathic, whereas secondary hyperhidrosis is commonly generalized and caused by an underlying medical condition or use of medications. Various surgical and nonsurgical therapies exist for primary hyperhidrosis. Although botulinum toxin is one of the deadliest toxins known, when used in small doses, it is one of the most effective therapies for primary hyperhidrosis. Botulinum toxin injections are widely used as a second-line primary hyperhidrosis treatment option once topical treatment strategies have failed. This article provides an overview of the commercially available botulinum toxin formulations and their applications in the treatment of primary hyperhidrosis.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | botulinum toxin
|
보툴리눔독소 주사 | dict | 4 |
MeSH Terms
Acetylcholine; Acetylcholine Release Inhibitors; Axilla; Botulinum Toxins, Type A; Dose-Response Relationship, Drug; Exocytosis; Humans; Hyperhidrosis; Injection Site Reaction; Injections, Intradermal; Neuromuscular Junction; Presynaptic Terminals; Quality of Life; Sweat Glands; Treatment Outcome; United States
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