Duration of Fecal Excretion of Clostridium Botulinum and Botulinum Neurotoxin in Patients Recovering from Infant Botulism.

The Journal of pediatrics 2023 Vol.258() p. 113396

Dabritz HA, Payne JR, Khouri JM

Abstract

This study sought to determine duration of fecal excretion of Clostridium botulinum organisms and neurotoxin after onset of infant botulism in 66 affected infants. Median excretion was longer for type A than type B patients (organisms: 5.9 vs 3.5 weeks, toxin: 4.8 vs 1.6 weeks, respectively). Toxin excretion always ceased before organism excretion. Antibiotic therapy did not affect duration of excretion.

MeSH Terms

Infant; Humans; Botulinum Toxins; Clostridium botulinum; Botulism; Feces; Clostridium