Effects of Anterior Fundoplication on Postoperative Dysphagia and Reflux After Laparoscopic Esophagocardiomyotomy for Pediatric Achalasia.

Journal of laparoendoscopic & advanced surgical techniques. Part A 2024 Vol.34(6) p. 535-540

French MP, Busing J, Acra S, Chen H, Stafman L, Zamora I, Holzman M, Lovvorn HN

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Abstract

Achalasia among children often fails endoscopic management (e.g., dilation, botulinum toxin). Laparoscopic esophagocardiomyotomy (L-ECM) is a standard intervention to relieve obstruction but can induce gastroesophageal reflux (GER). Concurrent anterior fundoplication (A-fundo) has been evaluated in randomized trials among adults, demonstrating mixed results on controlling postoperative GER without exacerbating dysphagia. Furthermore, evidence for the best approach among children remains sparse. We hypothesized that, among children undergoing L-ECM without mucosal violation, routine A-fundo would not improve postoperative GER control while exacerbating dysphagia. Observational data of 47 consecutive achalasia patients ≤18 years who received L-ECM (2002-2023) at a single academic institution were collected. Patient records were culled for demographics, achalasia characteristics, and outcomes. Two L-ECM groups were identified: with or without A-fundo. Patients were screened for postoperative dysphagia (additional procedures) and GER (new antireflux medications). Univariate independence testing was conducted to identify statistically significant variables. Among 47 patients undergoing L-ECM, 28 (59.6%) received concurrent A-fundo. Compared with patients undergoing L-ECM alone, patients with L-ECM/A-fundo had significantly longer hospital stays ( < .01) without statistically different rates of postoperative dysphagia ( = .81) or GER ( = .51). Five children (10.6%) experienced mucosal injury with L-ECM: 4 recognized intraoperatively received A-Fundo without subsequent leak; 1 mucosal injury was missed and did not receive A-Fundo, which subsequently leaked. In this largest observation of pediatric achalasia patients, A-fundo appeared clinically insignificant when determining contributors to control GER or exacerbate postoperative dysphagia. A-fundo should not be routinely adopted in children having L-ECM for achalasia without further multicenter analysis but appears beneficial in cases having inadvertent mucosal violation.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 1
해부 Anterior scispacy 1
해부 L-ECM → Laparoscopic esophagocardiomyotomy scispacy 1
해부 mucosal scispacy 1
합병증 gastroesophageal reflux scispacy 1
합병증 achalasia scispacy 1
합병증 A-fundo → anterior fundoplication scispacy 1
약물 GER → gastroesophageal reflux C0017168
Gastroesophageal reflux disease
scispacy 1
기법 endoscopic 내시경 dict 1
질환 Postoperative Dysphagia scispacy 1
질환 Achalasia C0014848
Esophageal Achalasia
scispacy 1
질환 gastroesophageal reflux C0017168
Gastroesophageal reflux disease
scispacy 1
질환 GER → gastroesophageal reflux C0017168
Gastroesophageal reflux disease
scispacy 1
질환 A-fundo → anterior fundoplication scispacy 1
질환 dysphagia C0011168
Deglutition Disorders
scispacy 1
질환 achalasia patients ≤18 scispacy 1
기타 children scispacy 1
기타 GER → gastroesophageal reflux scispacy 1

MeSH Terms

Humans; Esophageal Achalasia; Fundoplication; Female; Male; Child; Postoperative Complications; Gastroesophageal Reflux; Laparoscopy; Deglutition Disorders; Adolescent; Child, Preschool; Retrospective Studies; Treatment Outcome; Cardia; Esophagus

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