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Foodborne Botulism Type F: A Rare Presentation of Neurologic Manifestation and Successful Management.

Cureus 2024 Vol.16(6) p. e62964

Maharjan N, Chirumamilla Y, Karki B, Berrou M, Mcdonald PJ

Abstract

Botulism is a neuroparalytic syndrome resulting from the systemic effects of an exoneurotoxin produced by gram-positive, rod-shaped, spore-forming, obligate anaerobic bacterium . Here, we present the case of a 40-year-old male, presenting with a sudden onset of abdominal pain associated with vomiting. He was admitted for conservative management once the CT of the abdomen and pelvis revealed partial small bowel obstruction with no signs of bowel perforation or ischemia. However, the next day, the patient had a cardiac arrest thought to be secondary to respiratory arrest. The return of spontaneous circulation was achieved after two cycles of cardiopulmonary resuscitation. The patient developed quadriplegia, areflexia, and bilateral ophthalmoplegia. He was empirically treated with pyridostigmine, intravenous immunoglobulin (IVIG), and botulinum antitoxin. Stool polymerase chain reaction (PCR) testing resulted positive for  toxin type F. The patient ultimately recovered with botulinum antitoxin and a month of physical and speech therapy. Our case highlights that clinicians should consider botulism as a differential and emphasize the importance of early diagnosis for effective management and prognosis.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 abdominal scispacy 1
해부 pelvis scispacy 1
해부 bowel scispacy 1
해부 cardiac scispacy 1
해부 intravenous immunoglobulin ( scispacy 1
합병증 abdomen scispacy 1
약물 Botulism Type F scispacy 1
약물 pyridostigmine C0034261
pyridostigmine
scispacy 1
약물 IVIG → intravenous immunoglobulin scispacy 1
질환 Botulism C0006057
Botulism
scispacy 1
질환 neuroparalytic syndrome scispacy 1
질환 abdominal pain C0000737
Abdominal Pain
scispacy 1
질환 vomiting C0042963
Vomiting
scispacy 1
질환 partial small bowel obstruction C0281936
Partial obstruction of small bowel
scispacy 1
질환 ischemia C0022116
Ischemia
scispacy 1
질환 cardiac arrest C0018790
Cardiac Arrest
scispacy 1
질환 respiratory arrest C0162297
Respiratory arrest
scispacy 1
질환 quadriplegia C0034372
Quadriplegia
scispacy 1
질환 areflexia C0234146
Absent reflex
scispacy 1
기타 Type F: A scispacy 1
기타 cardiopulmonary scispacy 1
기타 botulinum antitoxin scispacy 1
기타 Stool polymerase chain scispacy 1