Frontal fibrosing alopecia in postmenopausal women.
💡 한 문장 핵심
폐경 후 여성에서의 전두부 섬유화 탈모.
4/5 보강
TL;DR
Frontal fibrosing alopecia may represent a variety of lichen planopilaris with selective involvement of certain androgen-dependent areas and the effectiveness of finasteride in some patients may indicate that androgens might be partially responsible of the pathogenesis of the disease.
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
9 patients also had partial or total loss of the eyebrows.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
It is interesting to note that some of the patients treated with finasteride (2.5 mg/d) showed an arrest in the progression of the disease. Even if there is no proof for a hormonal basis of the disease, the effectiveness of finasteride in some patients may indicate that androgens might be partially responsible of the pathogenesis of the disease.
📑 코퍼스 인용 관계
· 인용됨 29
📑 인용한 논문 (6) ▾
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- The Use of Light-Based Therapies in the Treatment of Alopecia. Journal of cosmetic dermatology · 2025
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- Frontal Fibrosing Alopecia and Reproductive Health: Assessing the Role of Sex Hormones in … Journal of personalized medicine · 2024
- Applications and efficacy of minoxidil in dermatology. Skin health and disease · 2024
- Clinicopathological Features of Frontal Fibrosing Alopecia (FFA) in 26 females: A Retrospe… Iranian journal of pathology · 2024
연도별 인용 (2012–2025) · 합계 168
OpenAlex 토픽 ·
Hair Growth and Disorders
melanin and skin pigmentation
Facial Rejuvenation and Surgery Techniques
Abstract 🌐 Abstract
[BACKGROUND] Frontal fibrosing alopecia is a variety of cicatricial alopecia characterized by a band of frontal/frontoparietal hair recession and marked decrease or a complete loss of the eyebrows, typically observed in women who are postmenopausal.
[OBJECTIVE] The purpose of this study was to report clinical and histopathologic findings and results of treatment in a group of women affected by the disease.
[METHOD] A total of 14 women with alopecia of the frontal hairline were evaluated from June 2000 through July 2003 in our outpatient consultation for hair disorders.
[RESULTS] Clinical examination revealed a band of symmetric recession of the frontoparietal hairline extending to the preauricular areas associated with loss of follicular orifices, mild skin atrophy, and perifollicular erythema at the scalp margin. In all, 9 patients also had partial or total loss of the eyebrows. The histologic features of the scalp specimens were similar in all our patients with a reduction of the number of hair follicles, and a high number of intermediate and velluslike follicles. Intemediate and velluslike follicles were more commonly affected than terminal follicles by the lymphocytic inflammatory infiltrate and perifollicular fibrosis.
[CONCLUSION] Frontal fibrosing alopecia is a cicatricial alopecia that follows destruction of hair follicles by an inflammatory lymphocytic infiltrate that is localized around the upper portion of the hair follicle. It differs from lichen planopilaris because the lymphocytic infiltrate and fibrosis affect selectively the intermediate and the velluslike follicles of the frontal margin and eyebrows. The reason for this selective involvement is still unknown. Frontal fibrosing alopecia may represent a variety of lichen planopilaris with selective involvement of certain androgen-dependent areas. The affected follicles may have typical biologic markers that could explain the clinical and histologic features found in the disease. It is interesting to note that some of the patients treated with finasteride (2.5 mg/d) showed an arrest in the progression of the disease. Even if there is no proof for a hormonal basis of the disease, the effectiveness of finasteride in some patients may indicate that androgens might be partially responsible of the pathogenesis of the disease.
[OBJECTIVE] The purpose of this study was to report clinical and histopathologic findings and results of treatment in a group of women affected by the disease.
[METHOD] A total of 14 women with alopecia of the frontal hairline were evaluated from June 2000 through July 2003 in our outpatient consultation for hair disorders.
[RESULTS] Clinical examination revealed a band of symmetric recession of the frontoparietal hairline extending to the preauricular areas associated with loss of follicular orifices, mild skin atrophy, and perifollicular erythema at the scalp margin. In all, 9 patients also had partial or total loss of the eyebrows. The histologic features of the scalp specimens were similar in all our patients with a reduction of the number of hair follicles, and a high number of intermediate and velluslike follicles. Intemediate and velluslike follicles were more commonly affected than terminal follicles by the lymphocytic inflammatory infiltrate and perifollicular fibrosis.
[CONCLUSION] Frontal fibrosing alopecia is a cicatricial alopecia that follows destruction of hair follicles by an inflammatory lymphocytic infiltrate that is localized around the upper portion of the hair follicle. It differs from lichen planopilaris because the lymphocytic infiltrate and fibrosis affect selectively the intermediate and the velluslike follicles of the frontal margin and eyebrows. The reason for this selective involvement is still unknown. Frontal fibrosing alopecia may represent a variety of lichen planopilaris with selective involvement of certain androgen-dependent areas. The affected follicles may have typical biologic markers that could explain the clinical and histologic features found in the disease. It is interesting to note that some of the patients treated with finasteride (2.5 mg/d) showed an arrest in the progression of the disease. Even if there is no proof for a hormonal basis of the disease, the effectiveness of finasteride in some patients may indicate that androgens might be partially responsible of the pathogenesis of the disease.
Frontal fibrosing alopecia may represent a variety of lichen planopilaris with selective involvement of certain androgen-dependent areas and the effectiveness of finasteride in some patients may indic
APA 7
Tosti, A., Piraccini, B. M., Iorizzo, M., & Misciali, C. (2005). Frontal fibrosing alopecia in postmenopausal women.. Journal of the American Academy of Dermatology, 52(1), 55-60. https://doi.org/10.1016/j.jaad.2004.05.014
Vancouver
Tosti A, Piraccini BM, Iorizzo M, Misciali C. Frontal fibrosing alopecia in postmenopausal women. Jour. Amer. Acad. Derm.. 2005;52(1):55-60. doi:10.1016/j.jaad.2004.05.014
AMA 11
Tosti A, Piraccini BM, Iorizzo M, Misciali C. Frontal fibrosing alopecia in postmenopausal women. Jour. Amer. Acad. Derm.. 2005;52(1):55-60. doi:10.1016/j.jaad.2004.05.014
Chicago
Tosti, A., Piraccini, B. M., Iorizzo, M., and Misciali, C.. 2005. "Frontal fibrosing alopecia in postmenopausal women." Journal of the American Academy of Dermatology 52 (1): 55-60. https://doi.org/10.1016/j.jaad.2004.05.014
MLA 9
Tosti, A., et al. "Frontal fibrosing alopecia in postmenopausal women." Journal of the American Academy of Dermatology, vol. 52, no. 1, 2005, pp. 55-60. doi:10.1016/j.jaad.2004.05.014.
PMID
15627081 ↗
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 8/8 (100%)
· 참조 0편 · 후속 8편
이 논문을 인용한 후속 연구 20
- Minoxidil and its use in hair disorders: a review.
- Female pattern hair loss.
- Frontal Fibrosing Alopecia: A Review.
- Frontal fibrosing alopecia treatment options.
- Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment.
- Frontal Fibrosing Alopecia and Vitiligo: Coexistence or True Association?
- Finasteride-mediated hair regrowth and reversal of atrophy in a patient with frontal fibrosing alope…
- Frontal fibrosing alopecia: efficacy of treatment modalities.
- Frontal fibrosing alopecia: A review of disease pathogenesis.
- Frontal Fibrosing Alopecia Severity Index: A Trichoscopic Visual Scale That Correlates Thickness of …
- Eyebrow and Eyelash Alopecia: A Clinical Review.
- Optimal Management of Frontal Fibrosing Alopecia: A Practical Guide.
- The "Starry Night Sky Sign" Using Ultraviolet-Light-Enhanced Trichoscopy: A New Sign That May Predic…
- Bitemporal Scalp Hair Loss: Differential Diagnosis of Nonscarring and Scarring Conditions.
- Frontal Fibrosing Alopecia: Role of Dermoscopy in Differential Diagnosis.
- Enhanced Insights into Frontal Fibrosing Alopecia: Advancements in Pathogenesis Understanding and Ma…
- Applications and efficacy of minoxidil in dermatology.
- Chronic lymphocytic leukemia skin infiltrates presenting as eyebrow alopecia and erythematous prurit…
- Cicatricial Alopecia with Particular Trichoscopic and Histopathological Features.
- Frontal Fibrosing Alopecia: A Comprehensive Guide for Cosmetic Dermatologists.
같은 제1저자의 인용 많은 논문 (5)
- Finasteride and the hair cycle.
- Treatment strategies for alopecia.
- Permanent alopecia after busulfan chemotherapy.
- Follicular red dots: a novel dermoscopic pattern observed in scalp discoid lupus erythematosus.
- Evaluation of sexual function in subjects taking finasteride for the treatment of androgenetic alopecia.
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- 피나스테리드가 전립선암 발생에 미치는 영향.
- COVID-19의 50가지 이상의 장기 후유증: 체계적 문헌고찰 및 메타분석.
- 양성 전립선 비대증의 임상적 진행에 대한 doxazosin, finasteride 및 병용 요법의 장기 효과.
- 양성 전립선 비대증 환자에서 finasteride의 효과. The Finasteride Study Group.
- 양성 전립선 비대증 남성에서 급성 요폐의 위험과 수술적 치료 필요성에 대한 finasteride의 효과. Finasteride Long-Term Efficacy and Safety Study Group.
- 원형 탈모.