Frontal fibrosing alopecia: a review of 60 cases.
💡 한 문장 핵심
전두부 섬유화 탈모: 60예에 대한 고찰.
4/5 보강
TL;DR
Frontal fibrosing alopecia is a clinically distinctive condition, the prevalence of which appears to be increasing and has a generally poor response to treatment.
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
60 patients with FFA.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
It has a generally poor response to treatment. The origin remains uncertain.
📑 코퍼스 인용 관계
· 인용됨 48
📑 인용한 논문 (6) ▾
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- Frontal Fibrosing Alopecia: A Comprehensive Review with Recent Updates. Indian journal of dermatology · 2025
- Histopathological characterization of inflammatory interparietal involvement in frontal fi… Frontiers in medicine · 2025
- Frontal Fibrosing Alopecia: An Update. American journal of clinical dermatology · 2025
- Is there a Rationale for the Use of Lymecycline for Frontal Fibrosing Alopecia? Dermatology practical & conceptual · 2024
- Frontal Fibrosing Alopecia and Reproductive Health: Assessing the Role of Sex Hormones in … Journal of personalized medicine · 2024
연도별 인용 (2012–2026) · 합계 219
OpenAlex 토픽 ·
Hair Growth and Disorders
Mesenchymal stem cell research
Systemic Sclerosis and Related Diseases
Abstract 🌐 Abstract
[BACKGROUND] Frontal fibrosing alopecia (FFA) is a variant of lichen planopilaris primarily affecting postmenopausal women, with a predilection for the frontotemporal hairline.
[OBJECTIVES] We sought to examine possible causal associations and review the clinical features, natural history, and response to treatment of patients with FFA attending a specialist hair clinic.
[METHODS] This was a case note review of 60 patients with FFA.
[RESULTS] The number of patients with FFA seen has increased over the last decade. All were Caucasian women, with significantly above-average affluence scores and were less likely to be smokers. The mean age at presentation was 64 years and average disease duration was 3.4 years (range: 6 months-30 years). Three patients were premenopausal. All patients had frontotemporal involvement, with follicular hyperkeratosis, scarring, and variable perifollicular erythema. Several patients had more unusual patterns: 8 had extensive parietal involvement, 4 had occipital involvement, 1 had asymmetric frontal involvement, and 5 had typical FFA associated with diffuse scalp lichen planopilaris. Eyebrow loss was documented in 73%, eyelash loss in 3%, and body hair loss in 25%. Almost all patients had been treated with superpotent topical steroids. Other treatments included topical calcineurin inhibitors; intralesional triamcinolone acetate; phototherapy; hydroxychloroquine; lymecycline; and prednisolone. Although some treatments may reduce inflammation, their efficacy in controlling the progress of the alopecia was uncertain.
[LIMITATIONS] This is a retrospective review.
[CONCLUSIONS] FFA is a clinically distinctive condition, the prevalence of which appears to be increasing. It has a generally poor response to treatment. The origin remains uncertain.
[OBJECTIVES] We sought to examine possible causal associations and review the clinical features, natural history, and response to treatment of patients with FFA attending a specialist hair clinic.
[METHODS] This was a case note review of 60 patients with FFA.
[RESULTS] The number of patients with FFA seen has increased over the last decade. All were Caucasian women, with significantly above-average affluence scores and were less likely to be smokers. The mean age at presentation was 64 years and average disease duration was 3.4 years (range: 6 months-30 years). Three patients were premenopausal. All patients had frontotemporal involvement, with follicular hyperkeratosis, scarring, and variable perifollicular erythema. Several patients had more unusual patterns: 8 had extensive parietal involvement, 4 had occipital involvement, 1 had asymmetric frontal involvement, and 5 had typical FFA associated with diffuse scalp lichen planopilaris. Eyebrow loss was documented in 73%, eyelash loss in 3%, and body hair loss in 25%. Almost all patients had been treated with superpotent topical steroids. Other treatments included topical calcineurin inhibitors; intralesional triamcinolone acetate; phototherapy; hydroxychloroquine; lymecycline; and prednisolone. Although some treatments may reduce inflammation, their efficacy in controlling the progress of the alopecia was uncertain.
[LIMITATIONS] This is a retrospective review.
[CONCLUSIONS] FFA is a clinically distinctive condition, the prevalence of which appears to be increasing. It has a generally poor response to treatment. The origin remains uncertain.
Frontal fibrosing alopecia is a clinically distinctive condition, the prevalence of which appears to be increasing and has a generally poor response to treatment.
APA 7
MacDonald, A., Clark, C., & Holmes, S. (2012). Frontal fibrosing alopecia: A review of 60 cases.. Journal of the American Academy of Dermatology, 67(5), 955-61. https://doi.org/10.1016/j.jaad.2011.12.038
Vancouver
MacDonald A, Clark C, Holmes S. Frontal fibrosing alopecia: a review of 60 cases. Jour. Amer. Acad. Derm.. 2012;67(5):955-61. doi:10.1016/j.jaad.2011.12.038
AMA 11
MacDonald A, Clark C, Holmes S. Frontal fibrosing alopecia: a review of 60 cases. Jour. Amer. Acad. Derm.. 2012;67(5):955-61. doi:10.1016/j.jaad.2011.12.038
Chicago
MacDonald, A., Clark, C., and Holmes, S.. 2012. "Frontal fibrosing alopecia: a review of 60 cases." Journal of the American Academy of Dermatology 67 (5): 955-61. https://doi.org/10.1016/j.jaad.2011.12.038
MLA 9
MacDonald, A., et al. "Frontal fibrosing alopecia: a review of 60 cases." Journal of the American Academy of Dermatology, vol. 67, no. 5, 2012, pp. 955-61. doi:10.1016/j.jaad.2011.12.038.
PMID
22503342 ↗
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 8/8 (100%)
· 참조 0편 · 후속 8편
이 논문을 인용한 후속 연구 20
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- Association of Inflammation With Progression of Hair Loss in Women With Frontal Fibrosing Alopecia.
- Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment.
- Perifollicular erythema as a trichoscopy sign of progression in frontal fibrosing alopecia.
- Finasteride-mediated hair regrowth and reversal of atrophy in a patient with frontal fibrosing alope…
- Frontal Fibrosing Alopecia and Increased Scalp Sweating: Is Neurogenic Inflammation the Common Link?
- Frontal fibrosing alopecia: efficacy of treatment modalities.
- Dysbiosis and Enhanced Beta-Defensin Production in Hair Follicles of Patients with Lichen Planopilar…
- Familial Cicatricial Alopecia: Report of Familial Frontal Fibrosing Alopecia and Fibrosing Alopecia …
- Study of the Thyroid Profile of Patients with Alopecia.
- Graft versus Host Disease Presenting as Fibrosing Alopecia in a Pattern Distribution: A Model for Pa…
- Case Report of Connubial Frontal Fibrosing Alopecia.
- Frontal Fibrosing Alopecia Severity Index: A Trichoscopic Visual Scale That Correlates Thickness of …
- Frontal Alopecia after Repeated Botulinum Toxin Type A Injections for Forehead Wrinkles: An Underest…
- Frontal fibrosing alopecia and personal care product use: a systematic review and meta-analysis.
- Frontal Fibrosing Alopecia: An Observational Single-Center Study of 306 Cases.
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