Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University.
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👥 코호트
4/5 보강
TL;DR
A number of treatments, including topical and intralesional steroids, antibiotics, and immunomodulators, were used with disappointing results in most patients, but the majority of patients on dutasteride experienced disease stabilization and no therapy was associated with significant hair regrowth.
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: FFA seen at an academic hair loss clinic and their responses to various therapeutic interventions
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Without clear understanding of the pathogenesis and evolution of this condition, it is not surprising that treatments to date have been minimally or not effective. At our institution, dutasteride was most effective in halting disease progression, although no therapy was associated with significant hair regrowth.
📑 코퍼스 인용 관계
· 인용됨 6
📑 인용한 논문 (6) ▾
- Frontal Fibrosing Alopecia: A Comprehensive Review with Recent Updates. Indian journal of dermatology · 2025
- The Frontal Fibrosing Alopecia Treatment Dilemma. Journal of clinical medicine · 2024
- Clinicopathological Features of Frontal Fibrosing Alopecia (FFA) in 26 females: A Retrospe… Iranian journal of pathology · 2024
- Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hai… Journal of clinical medicine · 2023
- Frontal Fibrosing Alopecia: An Observational Single-Center Study of 306 Cases. Life (Basel, Switzerland) · 2023
- Clinical and Dermoscopic Approaches to Diagnosis of Frontal Fibrosing Alopecia: Results Fr… Dermatology practical & conceptual · 2022
연도별 인용 (2014–2025) · 합계 121
OpenAlex 토픽 ·
Hair Growth and Disorders
Dermatologic Treatments and Research
Facial Rejuvenation and Surgery Techniques
A number of treatments, including topical and intralesional steroids, antibiotics, and immunomodulators, were used with disappointing results in most patients, but the majority of patients on dutaster
APA
Barry Ladizinski, Andrea Bazakas, et al. (2013). Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University.. Journal of the American Academy of Dermatology, 68(5), 749-55. https://doi.org/10.1016/j.jaad.2012.09.043
MLA
Barry Ladizinski, et al.. "Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University.." Journal of the American Academy of Dermatology, vol. 68, no. 5, 2013, pp. 749-55.
PMID
23375454 ↗
Abstract 한글 요약
[BACKGROUND] Frontal fibrosing alopecia (FFA) is a type of scarring hair loss primarily observed in postmenopausal women and characterized by fronto-tempero-parietal hairline recession, perifollicular erythema, and loss of eyebrows. The incidence is unknown, but the number of women presenting with this condition has significantly increased in recent years. No effective therapy has been established.
[OBJECTIVE] The purpose of this study is to present pertinent demographic and clinical findings of patients with FFA seen at an academic hair loss clinic and their responses to various therapeutic interventions.
[METHODS] Patients seen at the Duke University Hair Disorders Research and Treatment Center, Durham, NC, between 2004 and 2011 who met FFA inclusion criteria and signed an informed consent form for participation in the Duke University Hair Disorders Research and Treatment Center database were included in this review.
[RESULTS] Nineteen female patients with FFA met our inclusion criteria, the majority of whom were white and postmenopausal. A number of treatments, including topical and intralesional steroids, antibiotics, and immunomodulators, were used with disappointing results in most patients. However, the majority of patients on dutasteride experienced disease stabilization.
[LIMITATIONS] This was a retrospective review and outside clinic records were occasionally incomplete.
[CONCLUSIONS] FFA is an increasingly common form of scarring hair loss, but the origin remains unknown. Without clear understanding of the pathogenesis and evolution of this condition, it is not surprising that treatments to date have been minimally or not effective. At our institution, dutasteride was most effective in halting disease progression, although no therapy was associated with significant hair regrowth.
[OBJECTIVE] The purpose of this study is to present pertinent demographic and clinical findings of patients with FFA seen at an academic hair loss clinic and their responses to various therapeutic interventions.
[METHODS] Patients seen at the Duke University Hair Disorders Research and Treatment Center, Durham, NC, between 2004 and 2011 who met FFA inclusion criteria and signed an informed consent form for participation in the Duke University Hair Disorders Research and Treatment Center database were included in this review.
[RESULTS] Nineteen female patients with FFA met our inclusion criteria, the majority of whom were white and postmenopausal. A number of treatments, including topical and intralesional steroids, antibiotics, and immunomodulators, were used with disappointing results in most patients. However, the majority of patients on dutasteride experienced disease stabilization.
[LIMITATIONS] This was a retrospective review and outside clinic records were occasionally incomplete.
[CONCLUSIONS] FFA is an increasingly common form of scarring hair loss, but the origin remains unknown. Without clear understanding of the pathogenesis and evolution of this condition, it is not surprising that treatments to date have been minimally or not effective. At our institution, dutasteride was most effective in halting disease progression, although no therapy was associated with significant hair regrowth.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
- 5-alpha Reductase Inhibitors
- Adult
- Aged
- Alopecia
- Anti-Bacterial Agents
- Azasteroids
- Cicatrix
- Dutasteride
- Enzyme Inhibitors
- Eyebrows
- Female
- Fibrosis
- Forehead
- Hospitals
- University
- Humans
- Hydroxychloroquine
- Immunosuppressive Agents
- Lichen Planus
- Methotrexate
- Middle Aged
- Minocycline
- Osteoporosis
- Postmenopausal
… 외 4개
인용 관계
그래프 OA 노드: 6/6 (100%)
· 참조 0편 · 후속 6편
이 논문을 인용한 후속 연구 6
- Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hair Loss Dis…
- Frontal Fibrosing Alopecia: An Observational Single-Center Study of 306 Cases.
- Clinical and Dermoscopic Approaches to Diagnosis of Frontal Fibrosing Alopecia: Results From a Multi…
- The Frontal Fibrosing Alopecia Treatment Dilemma.
- Frontal Fibrosing Alopecia: A Comprehensive Review with Recent Updates.
- Clinicopathological Features of Frontal Fibrosing Alopecia (FFA) in 26 females: A Retrospective Stud…
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