Observation of Safety and Efficacy of Botulinum Toxin Type A in the Treatment of Tear Troughs and Mild Yelid Bags.

Journal of cosmetic dermatology 2025 Vol.24(6) p. e70253

Zhou S, Liu H, Pan Z, Pan F, Liang Q, Qiu H, Wu B, Zhang L, Zhou X

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Abstract

[OBJECTIVE] To evaluate the safety and efficacy of Botulinum Toxin Type A (BTX-A) injection for the treatment of tear troughs.

[METHOD] This study included patients with tear troughs rated as Grade 1-2 on the Barton Aesthetic Scale, who were treated between September 2023 and September 2024. These patients underwent intradermal injections of Botulinum Toxin Type A (BTX-A). Doctors conducted pre- and post-procedure assessments of the severity of tear troughs using the Barton Scale and TTRS (The Tear Trough Rating Scale). VISIA skin image analyzer (Canfield, USA) was utilized to compare the number of wrinkles, and facial scores and percentiles were calculated for objective evaluations before and after treatment. Additionally, doctors employed the Fitzpatrick Scale to assess periorbital wrinkles. This investigation was conducted as a prospective single-center study (PSS).

[RESULTS] All 42 patients completed the study. After treatment, there was a significant improvement in VISIA-measured wrinkle count, facial scores, and percentiles. Additionally, there were significant reductions in Barton, TTRS, and Fitzpatrick scores. One case of pseudo-eyelid bags was observed post-treatment, while no other complications such as diplopia, lower eyelid skin laxity, or other adverse effects were reported.

[CONCLUSION] BTX-A is effective in improving mild tear troughs while simultaneously reducing fine lines in the lower eyelid. Patients were highly satisfied with the improved appearance.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 3
해부 lower eyelid 눈꺼풀 dict 2
해부 Tear scispacy 1
해부 intradermal scispacy 1
해부 skin scispacy 1
해부 pseudo-eyelid scispacy 1
해부 eyelid 눈꺼풀 dict 1
합병증 wrinkles scispacy 1
합병증 periorbital wrinkles scispacy 1
합병증 wrinkle scispacy 1
합병증 eyelid skin scispacy 1
약물 PSS → prospective single-center study scispacy 1
약물 [OBJECTIVE] scispacy 1
약물 BTX-A → Botulinum Toxin Type A scispacy 1
약물 [CONCLUSION] BTX-A scispacy 1
질환 diplopia C0012569
Diplopia
scispacy 1
질환 Fitzpatrick scispacy 1
기타 Botulinum Toxin Type A scispacy 1
기타 patients scispacy 1

MeSH Terms

Humans; Botulinum Toxins, Type A; Skin Aging; Female; Middle Aged; Injections, Intradermal; Adult; Cosmetic Techniques; Treatment Outcome; Prospective Studies; Neuromuscular Agents; Male; Eyelids; Patient Satisfaction; Aged; Esthetics; Tears

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