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Foodborne Botulism Presenting With Isolated Cranial Nerve Involvement in a Young Adult.

Cureus 2025 Vol.17(11) p. e97040 🔓 OA Botulinum Toxin and Related Neurolog
TL;DR This case highlights the importance of early recognition of bulbar symptoms, the timely administration of empirical antitoxin therapy, and the role of ICU monitoring and emphasizes the need for high clinical suspicion in otherwise healthy young patients.
OpenAlex 토픽 · Botulinum Toxin and Related Neurological Disorders Peripheral Neuropathies and Disorders Hereditary Neurological Disorders

Barbosa M, Batista ME, Carneiro D, Cardoso S, Germano N

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This case highlights the importance of early recognition of bulbar symptoms, the timely administration of empirical antitoxin therapy, and the role of ICU monitoring and emphasizes the need for high c

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BibTeX ↓ RIS ↓
APA Miguel Barbosa, Mariana Batista, et al. (2025). Foodborne Botulism Presenting With Isolated Cranial Nerve Involvement in a Young Adult.. Cureus, 17(11), e97040. https://doi.org/10.7759/cureus.97040
MLA Miguel Barbosa, et al.. "Foodborne Botulism Presenting With Isolated Cranial Nerve Involvement in a Young Adult.." Cureus, vol. 17, no. 11, 2025, pp. e97040.
PMID 41426889

Abstract

A young man presented with progressive cranial nerve dysfunction following participation in a communal meal. Initial investigations and imaging were inconclusive; Guillain-Barré syndrome and viral encephalitis were considered in the differential diagnosis. He was admitted to the intensive care unit (ICU) due to the potential need for respiratory support. The progression of neurological dysfunction, combined with relevant dietary exposure, raised clinical suspicion for botulism. The patient was treated with heptavalent botulinum antitoxin, and serum testing later confirmed the presence of botulinum toxin type A. With multidisciplinary supportive care, he fully recovered without requiring mechanical ventilation. This case highlights the importance of early recognition of bulbar symptoms, the timely administration of empirical antitoxin therapy, and the role of ICU monitoring. It also underscores how non-specific early symptoms can delay diagnosis and emphasizes the need for high clinical suspicion in otherwise healthy young patients.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 1
해부 serum scispacy 1
해부 bulbar scispacy 1
합병증 Cranial Nerve scispacy 1
질환 Botulism C0006057
Botulism
scispacy 1
질환 cranial nerve dysfunction C3553482
Cranial nerve dysfunction
scispacy 1
질환 Guillain-Barré syndrome C0018378
Guillain-Barre Syndrome
scispacy 1
질환 viral encephalitis C0243010
Viral Encephalitis
scispacy 1
질환 neurological dysfunction C0027767
Nervous System Physiological Phenomena
scispacy 1
질환 antitoxin scispacy 1
질환 ICU → intensive care unit scispacy 1
기타 cranial nerve scispacy 1
기타 Guillain-Barré scispacy 1

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