Research progress in the use of botulinum toxin type a for post-stroke spasticity rehabilitation: a narrative review.

Annals of medicine 2025 Vol.57(1) p. 2521427

Xu Q, Xiao H, Zhu Z, Guan Y, Wang Y

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Abstract

[BACKGROUND] Stroke is a leading cause of long-term disability and death worldwide. Spasticity after stroke seriously affects patients' quality of life. If this state persists for a long time, it will lead to severe joint atrophy, reduced motor coordination, and even permanent disability. Therefore, clinical research has focused on the treatment of spasticity and the recovery of motor function after stroke.

[AIM] The aim of this paper is to explore the use of botulinum toxin type A in the rehabilitation of spasticity after stroke and to provide a theoretical basis for optimizing rehabilitation strategies, highlighting its potential value in reducing spasticity and improving motor function.

[METHOD] This article reviews the latest research progress on the application of BTX-A in spasticity after stroke, discusses the potential and challenges of BTX-A in reducing spasticity and improving motor function in patients with stroke.

[RESULT] Botulinum toxin type A (BTX-A) is a local muscle paralytic agent that has received extensive attention in recent years for its application in reducing muscle spasticity and promoting post-stroke rehabilitation.

[CONCLUSION] This article confirms that botulinum toxin type A has a significant clinical effect in treating muscle spasticity after stroke and also helps improve motor function restoration in patients. Studies have shown that botulinum toxin type A injections are effective in reducing spasticity and, when combined with rehabilitation training, can facilitate the recovery of motor function in post-stroke patients. Therefore, botulinum toxin type A has a broad application prospect in the rehabilitation of post-stroke spasticity.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 6
해부 muscle scispacy 1
약물 [BACKGROUND] scispacy 1
약물 BTX-A → Botulinum toxin type A scispacy 1
질환 post-stroke spasticity scispacy 1
질환 Stroke C0038454
Cerebrovascular accident
scispacy 1
질환 long-term disability scispacy 1
질환 death C0011065
Cessation of life
scispacy 1
질환 Spasticity C0026838
Muscle Spasticity
scispacy 1
질환 atrophy C0333641
Atrophic
scispacy 1
질환 reduced motor coordination scispacy 1
질환 muscle paralytic scispacy 1
질환 muscle spasticity C0026838
Muscle Spasticity
scispacy 1
질환 post-stroke scispacy 1
기타 botulinum toxin type scispacy 1
기타 patients scispacy 1
기타 joint scispacy 1
기타 botulinum toxin type A scispacy 1

MeSH Terms

Humans; Muscle Spasticity; Botulinum Toxins, Type A; Stroke; Stroke Rehabilitation; Neuromuscular Agents; Recovery of Function; Quality of Life; Treatment Outcome

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