Aesthetic Rehabilitation of Patients with Central and Peripheral Facial Palsy with Injectables (BNT-A, HA-Fillers and CaHa).

Journal of clinical medicine 2026 Vol.15(1)

Tsivgoulis A, Stefas E, Galatas G, Papagiannopoulou G, Fanouraki S, Stefanou MI, Vlotinou P, Zompola C, Tsivgoulis G, Theodorou A

관련 도메인

Abstract

Facial palsy constitutes a profoundly disabling condition, often leading to marked functional deficits and a decline in facial appearance, which substantially reduces the patient's quality of life. A combined therapy of botulinum toxin (BoNTA), hyaluronic acid (HA) and calcium hydroxylapatite (CaHA) appears promising in the pharmacological approach of these patients. We reported our single center experience of patients with facial palsy, either of central or peripheral etiology who were treated with the combination of BoNTA, HA and CaHA, during a 6-month period (January 2025-June 2025). Eight consecutive adult patients [mean age: 49.50 ± 7.95 years, 6 (75%) female] with facial palsy, either of central (4 patients) or peripheral (4 patients) etiology, received the combination of BoNTA, HA and CaHA. No serious adverse reactions were documented. Localized bruising and swelling at injection sites resolved without requiring any additional intervention. Facial Disability Index (FDI) was assessed both prior to and following treatment. The functional subscale increased from 65.63 ± 16.13 to 80.63 ± 10.50 (improvement rate = 24.4%, -value = 0.002), while the psychosocial subscale increased from 63.00 ± 17.34 to 74.50 ± 10.89 (improvement rate = 18.3%, -value = 0.004). Consequently, the total FDI score improved from 128.63 ± 28.92 to 155.13 ± 17.96 (overall improvement = 20.6%, -value = 0.001). The present case series underscores the potential therapeutic role of CaHA as an adjunct to BoNTA and HA injections in patients with central or peripheral facial palsy.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
재료 ha 히알루론산 dict 5
재료 caha 칼슘하이드록시아파타이트 dict 5
시술 botulinum toxin 보툴리눔독소 주사 dict 1
해부 peripheral scispacy 1
합병증 Peripheral Facial scispacy 1
재료 hyaluronic acid 히알루론산 dict 1
재료 calcium hydroxylapatite 칼슘하이드록시아파타이트 dict 1
약물 BoNTA scispacy 1
약물 calcium C0006675
calcium
scispacy 1
질환 Palsy C0522224
Paralysed
scispacy 1
질환 bruising C0009938
Contusions
scispacy 1
질환 swelling C0013604
Edema
scispacy 1
기타 Patients scispacy 1
기타 patient scispacy 1
기타 BoNTA scispacy 1
기타 HA injections scispacy 1

📑 인용 관계

🔗 함께 등장하는 도메인

이 논문이 속한 카테고리와 같은 논문에서 자주 함께 다뤄지는 카테고리들

관련 논문