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Efficacy of botulinum toxin type A for spasticity management and motor function in children with cerebral palsy: a systematic review and meta-analysis of randomized controlled trials.

메타분석 2/5 보강

Frontiers in neurology 📖 저널 OA 100% 2021~2026 2026 Vol.17() p. 1751493 OA Botulinum Toxin and Related Neurolog

TL;DR BoNT-A provides statistically significant short-term reductions in spasticity, with preliminary evidence suggesting potential for early functional gains when combined with rehabilitation, and evidence supports multimodal approaches combining pharmacological intervention with structured rehabilitation programs for optimal outcomes.

🔎 핵심 키워드 보툴리눔독소 주사 ×2 cerebral Upper limb limbs [BACKGROUND] Spasticity represents BoNT-A CI -0.43 between-dose 전체 NER ↓

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

892 participants.

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

Evidence supports multimodal approaches combining pharmacological intervention with structured rehabilitation programs for optimal outcomes. [SYSTEMATIC REVIEW REGISTRATION] https://www.crd.york.ac.uk/PROSPERO/view/CRD420251182969, identifier PROSPERO (CRD420251182969).

OpenAlex 토픽 · Botulinum Toxin and Related Neurological Disorders Cerebral Palsy and Movement Disorders Hereditary Neurological Disorders

Alghadier M, Alsuwayegh A

📖 무료 전문 🟢 PMC 전문 PMC12967947 🔓 OA PDF oa

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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