Beyond the Hot Comb: Updates in Epidemiology, Pathogenesis, and Treatment of Central Centrifugal Cicatricial Alopecia from 2011 to 2021.

American journal of clinical dermatology 2023 Vol.24(1) p. 81-88

George EA, Matthews C, Roche FC, Taylor SC

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Abstract

Central centrifugal cicatricial alopecia (CCCA) is a form of scarring alopecia that predominantly affects middle-aged women of African descent. Recent data suggest a multifactorial etiology of CCCA that is influenced by environmental and genetic factors. Emerging evidence regarding the genetic basis of the condition may elucidate new therapies. While topical and intralesional steroids and tetracycline antibiotics are the mainstay of treatment, refractory cases may be considered for hair transplantation. Emerging therapies using platelet-rich plasma, botanical formulas, and cosmetic procedures have shown promising results for the future management of CCA. As recent notable advances in CCCA have been achieved, this review provides an update on the epidemiology, pathophysiology, and management of CCCA.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 hair transplantation 모발이식 dict 1
해부 Centrifugal scispacy 1
해부 hair scispacy 1
해부 platelet-rich plasma scispacy 1
합병증 alopecia scispacy 1
약물 steroids C0038317
Steroids
scispacy 1
약물 tetracycline C0039644
tetracycline
scispacy 1
약물 platelet-rich C0370220
Platelet rich plasma
scispacy 1
약물 intralesional steroids scispacy 1
약물 CCA scispacy 1
질환 Alopecia C0002170
Alopecia
scispacy 1
기타 Comb scispacy 1
기타 women scispacy 1

MeSH Terms

Female; Humans; Middle Aged; Alopecia; Cicatrix

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