Lichen planopilaris following hair transplantation and face-lift surgery.

The British journal of dermatology 2012 Vol.166(3) p. 666-370

Chiang YZ, Tosti A, Chaudhry IH, Lyne L, Farjo B, Farjo N, Cadore de Farias D, Griffiths CE, Paus R, Harries MJ

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Abstract

Cosmetic surgical procedures, including hair transplantation and face-lift surgery, are becoming increasingly popular. However, there is very little information regarding the associated development of dermatological conditions following these procedures. Lichen planopilaris (LPP) is an uncommon inflammatory hair disorder of unknown aetiology that results in permanent alopecia and replacement of hair follicles with scar-like fibrous tissue. Frontal fibrosing alopecia (FFA), a variant of LPP, involves the frontal hairline and shares similar histological findings with those of LPP. We report 10 patients who developed LPP/FFA following cosmetic scalp surgery. Seven patients developed LPP following hair transplantation, and three patients developed FFA following face-lift surgery. In all cases there was no previous history of LPP or FFA. There is currently a lack of evidence to link the procedures of hair transplantation and cosmetic face-lift surgery to LPP and FFA, respectively. This is the first case series to describe this connection and to postulate the possible pathological processes underlying the clinical observation. Explanations include Koebner phenomenon induced by surgical trauma, an autoimmune process targeting an (as yet, unknown) hair follicle antigen liberated during surgery or perhaps a postsurgery proinflammatory milieu inducing hair follicle immune privilege collapse and follicular damage in susceptible individuals.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 hair transplantation 모발이식 dict 4
해부 hair scispacy 1
해부 scalp scispacy 1
해부 LPP → Lichen planopilaris scispacy 1
합병증 Lichen planopilaris scispacy 1
합병증 scar-like fibrous scispacy 1
합병증 frontal hairline scispacy 1
약물 FFA → Frontal fibrosing alopecia C4255374
Frontal fibrosing alopecia
scispacy 1
약물 LPP/FFA scispacy 1
질환 Lichen planopilaris C0023645
Lichen planus follicularis
scispacy 1
질환 alopecia C0002170
Alopecia
scispacy 1
질환 Frontal fibrosing alopecia C4255374
Frontal fibrosing alopecia
scispacy 1
질환 Koebner phenomenon scispacy 1
질환 trauma C0043251
Wounds and Injuries
scispacy 1
질환 LPP → Lichen planopilaris scispacy 1
기타 hair follicles scispacy 1
기타 Frontal fibrosing alopecia scispacy 1
기타 patients scispacy 1
기타 hair follicle antigen scispacy 1
기타 hair follicle scispacy 1
기타 follicular scispacy 1

MeSH Terms

Adult; Alopecia; Biopsy, Needle; Female; Hair; Humans; Lichen Planus; Male; Middle Aged; Postoperative Complications; Rhytidoplasty; Skin

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