In vitro study of the effects of ELF electric fields on gene expression in human epidermal cells.
1/5 보강
An acceleration of differentiation, at the expense of proliferation, is observed after exposure of various biological models to low frequency and low amplitude electric and electromagnetic fields.
APA
Collard JF, Mertens B, Hinsenkamp M (2011). In vitro study of the effects of ELF electric fields on gene expression in human epidermal cells.. Bioelectromagnetics, 32(1), 28-36. https://doi.org/10.1002/bem.20608
MLA
Collard JF, et al.. "In vitro study of the effects of ELF electric fields on gene expression in human epidermal cells.." Bioelectromagnetics, vol. 32, no. 1, 2011, pp. 28-36.
PMID
20809503 ↗
Abstract 한글 요약
An acceleration of differentiation, at the expense of proliferation, is observed after exposure of various biological models to low frequency and low amplitude electric and electromagnetic fields. Following these results showing significant modifications, we try to identify the biological mechanism involved at the cell level through microarray screening. For this study, we use epidermis cultures harvested from human abdominoplasty. Two platinum electrodes are used to apply the electric signal. The gene expressions of 38,500 well-characterized human genes are analyzed using Affymetrix(®) microarray U133 Plus 2.0 chips. The protocol is repeated on three different patients. After three periods of exposure, a total of 24 chips have been processed. After the application of ELF electric fields, the microarray analysis confirms a modification of the gene expression of epidermis cells. Particularly, four up-regulated genes (DKK1, TXNRD1, ATF3, and MME) and one down-regulated gene (MACF1) are involved in the regulation of proliferation and differentiation. Expression of these five genes was also confirmed by real-time rtPCR in all samples used for microarray analysis. These results corroborate an acceleration of cell differentiation at the expense of cell proliferation.
추출된 의학 개체 (NER)
시술
복부성형술
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | abdominoplasty
|
복부성형술 | dict | 1 | |
| 해부 | cell
|
scispacy | 1 | ||
| 해부 | epidermis cultures
|
scispacy | 1 | ||
| 해부 | epidermis cells
|
scispacy | 1 | ||
| 약물 | platinum
|
C0032207
platinum
|
scispacy | 1 | |
| 기타 | human epidermal cells
|
scispacy | 1 | ||
| 기타 | human abdominoplasty
|
scispacy | 1 | ||
| 기타 | human
|
scispacy | 1 | ||
| 기타 | DKK1
|
scispacy | 1 | ||
| 기타 | TXNRD1
|
scispacy | 1 | ||
| 기타 | ATF3
|
scispacy | 1 | ||
| 기타 | MME
|
scispacy | 1 | ||
| 기타 | MACF1
|
scispacy | 1 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
함께 등장하는 도메인
이 논문이 속한 카테고리와 같은 논문에서 자주 함께 다뤄지는 카테고리들
같은 제1저자의 인용 많은 논문 (1)
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- Advances in Cell-Mediated Drug Delivery for Dermatologic Diseases: Mechanisms and Current Applications.
- Investigating the expression changes of several key genes in prostate cancer cells under exposure to the ELF pulsed electromagnetic fields.
- Expression of HSP70 in Human Skin After Cryolipolysis Treatment.
- Full-thickness skin rejuvenation by a novel dual-length microneedle radiofrequency device: A proof-of-concept study using human skin.
- Effect of pdo facelift threads on facial skin tissues: An ultrasonographic analysis.
- Radiofrequency and pulsed electromagnetic field application following liposuction-Clinical evaluation of performance and safety.
📖 비슷한 OA 논문 — 같은 카테고리, 무료 전문 가능
- Does Scarpa's Fascia Preservation in Abdominoplasty Reduce Seroma? A Systematic Review.
- Scarpa Fascia Preservation to Reduce Seroma Rate on Massive Weight Loss Patients Undergoing Abdominoplasty: A Comparative Study.
- Dissection Technique for Abdominoplasty: A Prospective Study on Scalpel versus Diathermocoagulation (Coagulation Mode).
- Clinical Evaluation of 310 Abdominoplasties and Measurement of Scar Level.
- Classic Versus Scarpa-sparing abdominoplasty: An infrared thermographic comparative analysis.