[Silicone implants and breast cancer: real or fictitious problem? A case report and review of the literature].
Abstract
We present a case of breast cancer 9 years after subcutaneous mastectomy for bilateral phylloid tumor with silicone implants. The patient had a stage III adenocarcinoma (T4 N1 M0) at diagnosis; a modified radical mastectomy was done, followed by radiotherapy and chemotherapy. Later on, Tamoxifen was prescribed (positive hormone receptors). Reviewing the literature about this subject in a context of a moratorium of the Food and Drug Administration (FDA) in the United States recommending suspension of silicone breast implantation, we can propose several conclusions: Previous and recent studies did not show any direct relation between cancer and silicone implants for augmentation mammoplasty; on the contrary, a lower incidence of breast cancer is noted. Breast cancer incidence with silicone implants seems to be higher with reconstructive mammoplasty after mastectomy for benign disease (fibrocystic disease, dysplasia, phylloid tumor), or prophylactic reason, or malignancy (carcinoma in situ, lobular and multifocal carcinoma, early breast cancer...). This can be related to recurrence or cancer development on residual breast tissue. Breast cancer with silicone implants is of poorer prognosis because of the later diagnosis of the disease.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 해부 | breast
|
유방 | dict | 8 | |
| 시술 | augmentation mammoplasty
|
유방성형술 | dict | 1 | |
| 시술 | mammoplasty
|
유방성형술 | dict | 1 | |
| 해부 | subcutaneous
|
피하조직 | dict | 1 | |
| 합병증 | fibrocystic disease
|
scispacy | 1 | ||
| 합병증 | dysplasia
|
scispacy | 1 | ||
| 약물 | Silicone
|
C0037114
silicones
|
scispacy | 1 | |
| 약물 | Tamoxifen
|
C0039286
tamoxifen
|
scispacy | 1 | |
| 질환 | breast cancer
|
C0006142
Malignant neoplasm of breast
|
scispacy | 1 | |
| 질환 | phylloid tumor
|
scispacy | 1 | ||
| 질환 | adenocarcinoma
|
C0001418
Adenocarcinoma
|
scispacy | 1 | |
| 질환 | silicone breast
|
scispacy | 1 | ||
| 질환 | cancer
|
C0006826
Malignant Neoplasms
|
scispacy | 1 | |
| 질환 | benign disease
|
C0016034
Breast Fibrocystic Disease
|
scispacy | 1 | |
| 질환 | fibrocystic disease
|
C0010674
Cystic Fibrosis
|
scispacy | 1 | |
| 질환 | dysplasia
|
C0334044
Dysplasia
|
scispacy | 1 | |
| 질환 | malignancy
|
C0006826
Malignant Neoplasms
|
scispacy | 1 | |
| 질환 | carcinoma
|
C0007097
Carcinoma
|
scispacy | 1 | |
| 질환 | lobular
|
scispacy | 1 | ||
| 질환 | breast tissue
|
scispacy | 1 | ||
| 기타 | bilateral phylloid tumor
|
scispacy | 1 | ||
| 기타 | patient
|
scispacy | 1 |
MeSH Terms
Adenocarcinoma; Adult; Breast Implants; Breast Neoplasms; Female; Humans; Mastectomy, Subcutaneous; Neoplasms, Second Primary; Phyllodes Tumor; Silicones
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