Conservative treatment of lower pole breast cancers by bilateral mammoplasty and radiotherapy.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1998 Vol.24(6) p. 508-14

Nos C, Fitoussi A, Bourgeois D, Fourquet A, Salmon RJ, Clough KB

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Abstract

[AIMS] This series analyses the results of conservative surgery for large lower pole breast cancers by lumpectomy associated with a bilateral remodelling mammoplasty, in order to avoid residual deformities.

[METHODS] This retrospective study concerns 50 patients with a lower pole breast cancer treated between 1986 and 1996 by lumpectomy, mammoplasty and irradiation. The contralateral breast was immediately made symmetrical in all cases. The mean tumour size was 32.5 mm.

[RESULTS] The mean weight of the lumpectomy specimen was 270 g. Resection margins were tumour-free in 90% of cases. The main complication observed was delayed healing, thus postponing post-operative treatment in 6.5% of cases. The median follow-up was 48 months. The 5-year actuarial ipsilateral local recurrence rate was 7% and 5-year actuarial metastasis-free and overall survival rates were 81 and 97%, respectively. Cosmesis was satisfactory in 85% of patients. We observed better results when radiotherapy was performed after rather than prior to surgery (92 vs. 67%: NS).

[CONCLUSIONS] Performing a bilateral mammoplasty at the time of initial surgery for large breast cancers situated in the lower quadrants of the breast facilitates larger lumpectomies with good cosmetic results.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 breast 유방 dict 6
시술 mammoplasty 유방성형술 dict 4
해부 lower quadrants scispacy 1
합병증 lumpectomy specimen scispacy 1
약물 [CONCLUSIONS] scispacy 1
질환 lower pole breast cancers scispacy 1
질환 lower pole breast cancer scispacy 1
질환 tumour C0027651
Neoplasms
scispacy 1
질환 breast cancers C0006142
Malignant neoplasm of breast
scispacy 1
질환 breast cancer scispacy 1
기타 patients scispacy 1

MeSH Terms

Adult; Aged; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Mammaplasty; Mastectomy, Segmental; Middle Aged; Radiotherapy, Adjuvant; Retrospective Studies; Treatment Outcome

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