Breast reconstruction with deep inferior epigastric perforator flaps.

Annals of the Royal College of Surgeons of England 2012 Vol.94(8) p. 552-8

Cubitt J, Barber Z, Khan AA, Tyler M

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Abstract

[INTRODUCTION] Approximately 45,000 women are diagnosed with breast cancer in the UK each year. The success of screening and the introduction of adjuvant therapies have meant that prognosis is improving and an increasing number of patients are seeking reconstruction following mastectomy. The purpose of this study was to evaluate the deep inferior epigastric perforator (DIEP) flap reconstructions performed in Stoke Mandeville Hospital and, through analysis of complications, detail the evolution of the current care pathway.

[METHODS] A retrospective analysis was performed of all the DIEP flap reconstructions performed by the senior author (MT) between July 2003 and December 2010.

[RESULTS] Overall, 159 flaps were performed on 141 patients (including 36 bilateral flaps). The average patient age was 49 years (range: 28-70 years) and 13% of flaps were risk reducing for BRCA1/2. Twenty-six per cent of patients suffered one or more complication post-operatively, including systemic complications (pulmonary embolism 2%) and flap specific complications (partial flap necrosis 9%, reanastomosis 3%, fat necrosis 9%). Seventy-four per cent had further elective operations including nipple reconstruction (72%), contralateral breast reduction (36%) and scar revision (21%).

[CONCLUSIONS] DIEP flaps are a safe and reliable option for breast reconstructions. This series illustrates the significant leaning curve, with complications, operative time and ischaemic time reducing through the series and post-operative haemoglobin increasing. The complications experienced in this series of 159 flaps with no total flap loss provide the framework for the evolution of the current care pathway including pre-operative imaging, peri-operative deep vein thrombosis prophylaxis and analgesia.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 flap 피판재건술 dict 4
해부 breast 유방 dict 4
시술 breast reduction 유방성형술 dict 1
시술 diep flap 피판재건술 dict 1
시술 scar revision 흉터교정술 dict 1
해부 flaps scispacy 1
해부 reanastomosis 3 scispacy 1
해부 fat scispacy 1
해부 nipple scispacy 1
합병증 flap necrosis 괴사 dict 1
합병증 necrosis 괴사 dict 1
합병증 flaps scispacy 1
약물 [CONCLUSIONS] DIEP flaps scispacy 1
질환 breast cancer C0006142
Malignant neoplasm of breast
scispacy 1
질환 pulmonary embolism C0034065
Pulmonary Embolism
scispacy 1
질환 DIEP → deep inferior epigastric perforator scispacy 1
질환 vein thrombosis C0042487
Venous Thrombosis
scispacy 1
질환 BRCA1/2 scispacy 1
기타 women scispacy 1
기타 pulmonary embolism 2 scispacy 1

MeSH Terms

Adult; Aged; Breast Neoplasms; Female; Humans; Learning Curve; Length of Stay; Mammaplasty; Middle Aged; Operative Time; Postoperative Complications; Retrospective Studies; Surgical Flaps

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