Pyoderma gangrenosum following breast reduction: treatment with topical tacrolimus and steroids.
Abstract
[UNLABELLED] Pyoderma gangrenosum (PG) is a rare, noninfectious, inflammatory dermatosis usually associated with autoimmune disorders. Wounds may mimic a necrotizing infection, and the diagnosis is usually made after antibiotic therapy fails. Debridement may cause even larger wounds because of pathergy, so PG treatment consists of corticosteroids and local wound care. Pyoderma gangrenosum can be a devastating complication of breast and aesthetic surgery. We describe a case of PG following unilateral breast reduction that resulted in systemic inflammatory response; after treatment with prednisone and topical tacrolimus, the PG was resolved. The application of topical tacrolimus may reduce the need for prolonged corticosteroids.
[LEVEL OF EVIDENCE] 5.
[LEVEL OF EVIDENCE] 5.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 해부 | breast
|
유방 | dict | 3 | |
| 시술 | breast reduction
|
유방성형술 | dict | 2 | |
| 합병증 | Wounds
|
scispacy | 1 | ||
| 합병증 | wound
|
scispacy | 1 | ||
| 합병증 | infection
|
감염 | dict | 1 | |
| 약물 | tacrolimus
|
C0085149
tacrolimus
|
scispacy | 1 | |
| 약물 | steroids
|
C0038317
Steroids
|
scispacy | 1 | |
| 약물 | corticosteroids
|
C0001617
Adrenal Cortex Hormones
|
scispacy | 1 | |
| 약물 | prednisone
|
C0032952
prednisone
|
scispacy | 1 | |
| 질환 | Pyoderma gangrenosum
|
C0085652
Pyoderma Gangrenosum
|
scispacy | 1 | |
| 질환 | noninfectious
|
scispacy | 1 | ||
| 질환 | dermatosis
|
C0037274
Dermatologic disorders
|
scispacy | 1 | |
| 질환 | autoimmune disorders
|
C0004364
Autoimmune Diseases
|
scispacy | 1 |
MeSH Terms
Breast Diseases; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Mammaplasty; Middle Aged; Prednisone; Pyoderma Gangrenosum; Tacrolimus; Treatment Outcome
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