Platelet-rich plasma for androgenetic alopecia: a pilot study.
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TL;DR
A pilot study to explore the possible clinical benefit of injecting platelet-derived growth factors into the scalp of patients using a specific autologous blood concentrate may provide preliminary evidence that this treatment may induce some degree of clinical advantage for male- and female-pattern baldness.
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📑 인용한 논문 (6) ▾
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연도별 인용 (2014–2026) · 합계 131
OpenAlex 토픽 ·
Hair Growth and Disorders
Facial Rejuvenation and Surgery Techniques
Body Image and Dysmorphia Studies
A pilot study to explore the possible clinical benefit of injecting platelet-derived growth factors into the scalp of patients using a specific autologous blood concentrate may provide preliminary evi
- 95% CI 3.5-4.3
APA
Giovanni Schiavone, Desanka Raskovic, et al. (2014). Platelet-rich plasma for androgenetic alopecia: a pilot study.. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 40(9), 1010-9. https://doi.org/10.1097/01.DSS.0000452629.76339.2b
MLA
Giovanni Schiavone, et al.. "Platelet-rich plasma for androgenetic alopecia: a pilot study.." Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], vol. 40, no. 9, 2014, pp. 1010-9.
PMID
25111436 ↗
Abstract 한글 요약
[BACKGROUND] Androgenetic alopecia is a common condition, with severe attendant psychosocial implications, and for which it is difficult to obtain a satisfactory degree of clinical improvement.
[OBJECTIVE] To explore the possible clinical benefit of injecting platelet-derived growth factors into the scalp of patients using a specific autologous blood concentrate.
[MATERIALS AND METHODS] Two injections of a leukocyte platelet-rich plasma (L-PRP) with the addition of concentrated plasmatic proteins were administered at baseline and after 3 months (single spin at baseline and double-spin centrifugation at 3 months). Macrophotographs were taken at baseline and after 6 months, and 2 independent evaluators rated them using Jaeschke rating of clinical change.
[RESULTS] Sixty-four consecutive patients were enrolled. Some improvement was seen in all patients by 1 evaluator and in 62 by the other. The mean change in clinical rating was 3.2 (95% confidence interval [CI], 2.9-3.5) and 3.9 (95% CI, 3.5-4.3), and the proportion of patients reaching a clinically important difference was 40.6% and 54.7%, according to the 2 evaluators, respectively.
[CONCLUSION] Our pilot study may provide preliminary evidence that this treatment may induce some degree of clinical advantage for male- and female-pattern baldness. This may warrant the design of randomized controlled clinical trials to formally test this procedure.
[OBJECTIVE] To explore the possible clinical benefit of injecting platelet-derived growth factors into the scalp of patients using a specific autologous blood concentrate.
[MATERIALS AND METHODS] Two injections of a leukocyte platelet-rich plasma (L-PRP) with the addition of concentrated plasmatic proteins were administered at baseline and after 3 months (single spin at baseline and double-spin centrifugation at 3 months). Macrophotographs were taken at baseline and after 6 months, and 2 independent evaluators rated them using Jaeschke rating of clinical change.
[RESULTS] Sixty-four consecutive patients were enrolled. Some improvement was seen in all patients by 1 evaluator and in 62 by the other. The mean change in clinical rating was 3.2 (95% confidence interval [CI], 2.9-3.5) and 3.9 (95% CI, 3.5-4.3), and the proportion of patients reaching a clinically important difference was 40.6% and 54.7%, according to the 2 evaluators, respectively.
[CONCLUSION] Our pilot study may provide preliminary evidence that this treatment may induce some degree of clinical advantage for male- and female-pattern baldness. This may warrant the design of randomized controlled clinical trials to formally test this procedure.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 7/8 (88%)
· 참조 0편 · 후속 7편
이 논문을 인용한 후속 연구 12
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- Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review.
- Hair Transplant Practice Guidelines.
- Investigating the Safety and Efficacy of Platelet-Rich Plasma (PRP) Treatment for Female Androgeneti…
- Platelet-Rich Plasma in Androgenetic Alopecia: Is It Really Worth the Hype?
- Regenerative Medicine Treatments for Androgenetic Alopecia.
- Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth…
- Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia.