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Stem cells and their niches.

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Science (New York, N.Y.) 📖 저널 OA 35.6% 2021: 8/16 OA 2022: 1/11 OA 2023: 8/20 OA 2024: 9/22 OA 2025: 22/55 OA 2026: 27/79 OA 2021~2026 2006 Vol.311(5769) p. 1880-5 피인용 11회 cited 1,631 RCR 23.95 Cancer Cells and Metastasis
TL;DR The stem cell niche concept is discussed, recent progress is highlighted, and important unanswered questions are identified.
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PubMed DOI OpenAlex Semantic 마지막 보강 2026-05-10
📑 코퍼스 인용 관계 · 인용됨 11
📑 인용한 논문 (6) ▾
연도별 인용 (2012–2026) · 합계 837
OpenAlex 토픽 · Cancer Cells and Metastasis Mesenchymal stem cell research Pluripotent Stem Cells Research

Moore KA, Lemischka IR

Abstract

A constellation of intrinsic and extrinsic cellular mechanisms regulates the balance of self-renewal and differentiation in all stem cells. Stem cells, their progeny, and elements of their microenvironment make up an anatomical structure that coordinates normal homeostatic production of functional mature cells. Here we discuss the stem cell niche concept, highlight recent progress, and identify important unanswered questions. We focus on three mammalian stem cell systems where large numbers of mature cells must be continuously produced throughout adult life: intestinal epithelium, epidermal structures, and bone marrow.
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The stem cell niche concept is discussed, recent progress is highlighted, and important unanswered questions are identified.

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APA 7 Moore, K. A., & Lemischka, I. R. (2006). Stem cells and their niches.. Science (New York, N.Y.), 311(5769), 1880-5. https://doi.org/10.1126/science.1110542
Vancouver Moore KA, Lemischka IR. Stem cells and their niches. Science (New York, N.Y.). 2006;311(5769):1880-5. doi:10.1126/science.1110542
AMA 11 Moore KA, Lemischka IR. Stem cells and their niches. Science (New York, N.Y.). 2006;311(5769):1880-5. doi:10.1126/science.1110542
Chicago Moore, K. A., and Lemischka, I. R.. 2006. "Stem cells and their niches." Science (New York, N.Y.) 311 (5769): 1880-5. https://doi.org/10.1126/science.1110542
MLA 9 Moore, K. A., and Lemischka IR. "Stem cells and their niches." Science (New York, N.Y.), vol. 311, no. 5769, 2006, pp. 1880-5. doi:10.1126/science.1110542.
PMID 16574858 ↗

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