[Breast implant-associated anaplastic large cell lymphoma. Case report of an undiagnosed form, management and reconstruction (ALCL)].

Annales de chirurgie plastique et esthetique 2016 Vol.61(3) p. 223-30

Alhamad S, Guerid S, El Fakir EH, Biron P, Tourasse C, Delay E

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Abstract

Breast implant-associated anaplastic large cell lymphoma (ALCL) is an extremely rare disease. Is a new nosologic entity with a multifactorial origin and a wide occurrence delay after breast implantation. This article reports the case of a 60 years old patient with a progressive swelling of the right breast after aesthetic breast implants. Diagnostic was delayed because first surgeon was not familiar with the disease. Patient was then referred to us for management. We performed an implant removal and a complete capsulectomy. Pathologic report confirms the diagnostic. After one year and normal ultrasound evaluation, we reconstructed the breast with lipomodeling and mastopexy. Contralateral implant was also removed at time of reconstruction. Vast majority of breast implant-associated ALCL occurs at a time lapse of 11 to 15 years after implant augmentation, with a mean age of 63 years. Among the worldwide 173 cases reported in March 2015, smooth implants seem not to be at risk but 80% of cases were associated with macrotexturized implants. Clinical presentation and diagnostic tools are more and more published but there is to date no recommendation concerning reconstruction delay after implant removal for this pathology. We advise the realization of a breast ultrasound every three months during the first year and wait for a one-year period before reconstruction. In case of aesthetic surgery, mastopexia can be done to allow for glandular shaping. Lipomodeling is an excellent technique to correct the lack of volume due to implant removal. In case of reconstructive setting, implant can be replaced by flap procedure with lipomodeling if needed or lipomodeling alone if recipient site is favorable and patient has enough fat tissue. Contralateral implant should be removed during reconstruction time.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 breast 유방 dict 8
합병증 anaplastic large cell lymphoma 보형물연관 역형성대세포림프종 dict 2
시술 mastopexy 유방성형술 dict 1
시술 flap 피판재건술 dict 1
해부 smooth scispacy 1
해부 glandular scispacy 1
해부 fat tissue scispacy 1
질환 Breast implant-associated anaplastic large cell lymphoma C4528210
Breast implant-associated anaplastic large-cell lymphoma
scispacy 1
질환 ALCL → anaplastic large cell lymphoma C0206180
Ki-1+ Anaplastic Large Cell Lymphoma
scispacy 1
질환 swelling of the right breast scispacy 1
질환 breast implant-associated ALCL scispacy 1
기타 patient scispacy 1

MeSH Terms

Adipose Tissue; Breast Implants; Breast Neoplasms; Delayed Diagnosis; Device Removal; Diagnostic Errors; Female; Humans; Lymphoma, Large-Cell, Anaplastic; Mammaplasty; Middle Aged; Rare Diseases

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