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Use of a fibrinogen-thrombin sponge in rhinoplasty.

HNO 2018 Vol.66(2) p. 103-110

Berghaus A, San Nicoló M, Jacobi C

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[BACKGROUND] Although several methods have been described to address nasal dorsum augmentation and smoothing of irregularities in rhinoplasty, establishing the ideal method has proven controversial.

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BibTeX ↓ RIS ↓
APA Berghaus A, San Nicoló M, Jacobi C (2018). Use of a fibrinogen-thrombin sponge in rhinoplasty.. HNO, 66(2), 103-110. https://doi.org/10.1007/s00106-017-0414-0
MLA Berghaus A, et al.. "Use of a fibrinogen-thrombin sponge in rhinoplasty.." HNO, vol. 66, no. 2, 2018, pp. 103-110.
PMID 28939917

Abstract

[BACKGROUND] Although several methods have been described to address nasal dorsum augmentation and smoothing of irregularities in rhinoplasty, establishing the ideal method has proven controversial.

[OBJECTIVE] Here, we introduce a novel technique of cartilage grafting for nasal dorsum augmentation by wrapping cartilage in a fibrinogen- and thrombin-coated collagen patch called TachoSil®.

[MATERIAL AND METHODS] In a pilot study comprising ten cases, the use of the collagen patch was examined in various indications in rhinoplasty. Patients were clinically monitored for up to 8 months and photometric and sonographic documentation was performed pre- and postoperatively.

[RESULTS] In nine patients, the collagen patch was used for fixation of cartilage grafts in different indications: saddle nose deformities (n = 5), open roof (n = 1), nasal dorsum irregularities (n = 3). A diced cartilage graft enclosed by a bilayer of TachoSil® was applied in seven patients. Solid pieces of cartilage were either embedded in a bilayer of the collagen patch (n = 1) or covered by a monolayer (n = 1). Moreover, the collagen patch alone served as a soft tissue support in one patient with thin skin. Six patients were revision cases. All patients had uneventful healing without adverse events such as allergic reactions and infections.

[CONCLUSION] The collagen patch TachoSil® is eligible for various indications in rhinoplasty. It is a useful material predominantly for nasal dorsum augmentation by sandwiching diced or solid cartilage in the collagen patch, leading to better graft fixation and precise profile shaping. At the same time, TachoSil® helps with blood control. Follow-up studies will be performed to assess the material's long-term behavior.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 rhinoplasty 코성형술 dict 4
해부 nasal dorsum 콧등 dict 4
해부 cartilage scispacy 1
해부 cartilage grafts scispacy 1
해부 monolayer scispacy 1
해부 soft tissue scispacy 1
해부 skin scispacy 1
해부 graft scispacy 1
해부 blood scispacy 1
약물 [MATERIAL AND scispacy 1
질환 saddle nose deformities scispacy 1
질환 allergic reactions C0020517
Hypersensitivity
scispacy 1
질환 infections C0851162
Infections of musculoskeletal system
scispacy 1
질환 Solid scispacy 1
질환 solid cartilage scispacy 1
기타 fibrinogen-thrombin scispacy 1
기타 fibrinogen- scispacy 1
기타 thrombin-coated collagen patch scispacy 1
기타 TachoSil scispacy 1
기타 collagen scispacy 1

MeSH Terms

Fibrinogen; Humans; Pilot Projects; Rhinoplasty; Surgical Equipment; Thrombin

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