Early nasal reconstruction after skin-preserving excision of squamous cell carcinoma of the nasal vestibule.
【연구 목적】 비강 입술부(squamous cell carcinoma of the nasal vestibule, SCCNV)의 초기 단계에서 피부 보존적 절제술과 재건술이 종양학적 안전성, 심미적 결과, 기능적 회복 측면에서 타당한지 평가하고자 하였다.
- p-value p < 0.001
- 추적기간 5.4 years
APA
Federspil PA, Plinkert PK, Zaoui K (2020). Early nasal reconstruction after skin-preserving excision of squamous cell carcinoma of the nasal vestibule.. Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 73(9), 1683-1691. https://doi.org/10.1016/j.bjps.2020.03.001
MLA
Federspil PA, et al.. "Early nasal reconstruction after skin-preserving excision of squamous cell carcinoma of the nasal vestibule.." Journal of plastic, reconstructive & aesthetic surgery : JPRAS, vol. 73, no. 9, 2020, pp. 1683-1691.
PMID
32327374
Abstract
Surgery for early-stage squamous cell carcinoma of the nasal vestibule (SCCNV) may lead to facial disfigurement. We wanted to investigate if skin-preserving excision of SCCNV with reconstruction is oncologically, aesthetically, and functionally justifiable in cases with proximity to the skin. From 2010 to 2016, 16 patients underwent skin-preserving excision of T1-2 N0 SCCNV by a lateral rhinotomy approach at a tertiary referral center. The inner nose was reconstructed using a mucoperichondrial septal flap for the inner lining and a septal pivot flap and/or auricular cartilage grafting for the framework. Nasal appearance was measured on pre- and postoperative photographs. Median follow-up was 5.4 years. Three (19%) patients received adjuvant radiotherapy. Two (12.5%) recurrences occurred locally, but not at the site of preserved skin. The Kaplan-Meier estimate of local control rate after 5 years was 83%. All patients could be salvaged, giving an ultimate control rate of 100%. Nasal tip projection decreased by 6.7% (p < 0.001), and it was retained normal or near normal in 87.5% of patients. Nasal axis changed by 1.7° (p = 0.5). Nasal deviation occurred in 6.25% (1/16) of patients, and minor alar retraction in 6.25% of patients (1/16). Nasal breathing was normal or close to normal in 75% (12/16) of patients. Skin-preserving excision of SCCNV is oncologically justifiable in selected cases even in proximity to nasal skin. Early inner nasal reconstruction preserves nasal form and function to a high degree. This technique is a suitable alternative to rhinectomy and to avoid the sequelae of radiotherapy in selected cases.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | flap
|
피판재건술 | dict | 2 | |
| 해부 | skin
|
scispacy | 1 | ||
| 해부 | lateral
|
scispacy | 1 | ||
| 해부 | Nasal
|
scispacy | 1 | ||
| 해부 | nasal tip
|
코끝 | dict | 1 | |
| 해부 | alar
|
콧방울 | dict | 1 | |
| 합병증 | facial
|
scispacy | 1 | ||
| 재료 | auricular cartilage
|
이개연골 | dict | 1 | |
| 약물 | SCCNV
→ squamous cell carcinoma of the nasal vestibule
|
scispacy | 1 | ||
| 질환 | squamous cell carcinoma of the nasal vestibule
|
scispacy | 1 | ||
| 질환 | squamous cell carcinoma
|
scispacy | 1 | ||
| 질환 | early-stage squamous cell carcinoma
|
scispacy | 1 | ||
| 질환 | SCCNV
→ squamous cell carcinoma of the nasal vestibule
|
scispacy | 1 | ||
| 기타 | nasal
|
scispacy | 1 | ||
| 기타 | nasal vestibule
|
scispacy | 1 | ||
| 기타 | inner nose
|
scispacy | 1 | ||
| 기타 | inner nasal
|
scispacy | 1 |
MeSH Terms
Adult; Aged; Carcinoma, Squamous Cell; Cohort Studies; Ear Cartilage; Esthetics; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nose Neoplasms; Reoperation; Rhinoplasty; Surgical Flaps
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