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Early nasal reconstruction after skin-preserving excision of squamous cell carcinoma of the nasal vestibule.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS 2020 Vol.73(9) p. 1683-1691

Federspil PA, Plinkert PK, Zaoui K

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【연구 목적】 비강 입술부(squamous cell carcinoma of the nasal vestibule, SCCNV)의 초기 단계에서 피부 보존적 절제술과 재건술이 종양학적 안전성, 심미적 결과, 기능적 회복 측면에서 타당한지 평가하고자 하였다.

🔬 핵심 임상 통계 (초록에서 자동 추출 — 원문 검증 권장)
  • p-value p < 0.001
  • 추적기간 5.4 years

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BibTeX ↓ RIS ↓
APA Federspil PA, Plinkert PK, Zaoui K (2020). Early nasal reconstruction after skin-preserving excision of squamous cell carcinoma of the nasal vestibule.. Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 73(9), 1683-1691. https://doi.org/10.1016/j.bjps.2020.03.001
MLA Federspil PA, et al.. "Early nasal reconstruction after skin-preserving excision of squamous cell carcinoma of the nasal vestibule.." Journal of plastic, reconstructive & aesthetic surgery : JPRAS, vol. 73, no. 9, 2020, pp. 1683-1691.
PMID 32327374

Abstract

Surgery for early-stage squamous cell carcinoma of the nasal vestibule (SCCNV) may lead to facial disfigurement. We wanted to investigate if skin-preserving excision of SCCNV with reconstruction is oncologically, aesthetically, and functionally justifiable in cases with proximity to the skin. From 2010 to 2016, 16 patients underwent skin-preserving excision of T1-2 N0 SCCNV by a lateral rhinotomy approach at a tertiary referral center. The inner nose was reconstructed using a mucoperichondrial septal flap for the inner lining and a septal pivot flap and/or auricular cartilage grafting for the framework. Nasal appearance was measured on pre- and postoperative photographs. Median follow-up was 5.4 years. Three (19%) patients received adjuvant radiotherapy. Two (12.5%) recurrences occurred locally, but not at the site of preserved skin. The Kaplan-Meier estimate of local control rate after 5 years was 83%. All patients could be salvaged, giving an ultimate control rate of 100%. Nasal tip projection decreased by 6.7% (p < 0.001), and it was retained normal or near normal in 87.5% of patients. Nasal axis changed by 1.7° (p = 0.5). Nasal deviation occurred in 6.25% (1/16) of patients, and minor alar retraction in 6.25% of patients (1/16). Nasal breathing was normal or close to normal in 75% (12/16) of patients. Skin-preserving excision of SCCNV is oncologically justifiable in selected cases even in proximity to nasal skin. Early inner nasal reconstruction preserves nasal form and function to a high degree. This technique is a suitable alternative to rhinectomy and to avoid the sequelae of radiotherapy in selected cases.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 flap 피판재건술 dict 2
해부 skin scispacy 1
해부 lateral scispacy 1
해부 Nasal scispacy 1
해부 nasal tip 코끝 dict 1
해부 alar 콧방울 dict 1
합병증 facial scispacy 1
재료 auricular cartilage 이개연골 dict 1
약물 SCCNV → squamous cell carcinoma of the nasal vestibule scispacy 1
질환 squamous cell carcinoma of the nasal vestibule scispacy 1
질환 squamous cell carcinoma scispacy 1
질환 early-stage squamous cell carcinoma scispacy 1
질환 SCCNV → squamous cell carcinoma of the nasal vestibule scispacy 1
기타 nasal scispacy 1
기타 nasal vestibule scispacy 1
기타 inner nose scispacy 1
기타 inner nasal scispacy 1

MeSH Terms

Adult; Aged; Carcinoma, Squamous Cell; Cohort Studies; Ear Cartilage; Esthetics; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nose Neoplasms; Reoperation; Rhinoplasty; Surgical Flaps

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