The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis.
메타분석
4/5 보강
TL;DR
This meta‐analysis strongly suggests that minoxidil, finasteride, and low‐level laser light therapy are effective for promoting hair growth in men with androgenetic alopecia and that minxidil is effective in women with androgensetic alipecia.
📑 코퍼스 인용 관계
· 인용됨 125
📑 인용한 논문 (6) ▾
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연도별 인용 (2017–2026) · 합계 395
OpenAlex 토픽 ·
Hair Growth and Disorders
Ovarian function and disorders
Dermatologic Treatments and Research
Abstract 🌐 Abstract
[BACKGROUND] Androgenetic alopecia, or male pattern hair loss, is a hair loss disorder mediated by dihydrotestosterone, the potent form of testosterone. Currently, minoxidil and finasteride are Food and Drug Administration (FDA)-approved, and HairMax LaserComb, which is FDA-cleared, are the only treatments recognized by the FDA as treatments of androgenetic alopecia.
[OBJECTIVE] This systematic review and meta-analysis assesses the efficacy of nonsurgical treatments of androgenetic alopecia in comparison to placebo for improving hair density, thickness, growth (defined by an increased anagen:telogen ratio), or subjective global assessments done by patients and investigators.
[METHODS] A systematic review of randomized controlled trials was conducted. PubMed, Embase, and Cochrane were searched up to December 2016, with no lower limit on the year. We included only randomized controlled trials of good or fair quality based on the US Preventive Services Task Force quality assessment process.
[RESULTS] A meta-analysis was conducted separately for 5 groups of studies that tested the following hair loss treatments: low-level laser light therapy in men, 5% minoxidil in men, 2% minoxidil in men, 1 mg finasteride in men, and 2% minoxidil in women. All treatments were superior to placebo (P < .00001) in the 5 meta-analyses. Other treatments were not included because the appropriate data were lacking.
[LIMITATIONS] High heterogeneity in most studies.
[CONCLUSIONS] This meta-analysis strongly suggests that minoxidil, finasteride, and low-level laser light therapy are effective for promoting hair growth in men with androgenetic alopecia and that minoxidil is effective in women with androgenetic alopecia.
[OBJECTIVE] This systematic review and meta-analysis assesses the efficacy of nonsurgical treatments of androgenetic alopecia in comparison to placebo for improving hair density, thickness, growth (defined by an increased anagen:telogen ratio), or subjective global assessments done by patients and investigators.
[METHODS] A systematic review of randomized controlled trials was conducted. PubMed, Embase, and Cochrane were searched up to December 2016, with no lower limit on the year. We included only randomized controlled trials of good or fair quality based on the US Preventive Services Task Force quality assessment process.
[RESULTS] A meta-analysis was conducted separately for 5 groups of studies that tested the following hair loss treatments: low-level laser light therapy in men, 5% minoxidil in men, 2% minoxidil in men, 1 mg finasteride in men, and 2% minoxidil in women. All treatments were superior to placebo (P < .00001) in the 5 meta-analyses. Other treatments were not included because the appropriate data were lacking.
[LIMITATIONS] High heterogeneity in most studies.
[CONCLUSIONS] This meta-analysis strongly suggests that minoxidil, finasteride, and low-level laser light therapy are effective for promoting hair growth in men with androgenetic alopecia and that minoxidil is effective in women with androgenetic alopecia.
- p-value P < .00001
- 연구 설계 systematic review
This meta‐analysis strongly suggests that minoxidil, finasteride, and low‐level laser light therapy are effective for promoting hair growth in men with androgenetic alopecia and that minxidil is effec
APA 7
Adil, A., & Godwin, M. (2017). The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis.. Journal of the American Academy of Dermatology, 77(1), 136-141.e5. https://doi.org/10.1016/j.jaad.2017.02.054
Vancouver
Adil A, Godwin M. The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis. Jour. Amer. Acad. Derm.. 2017;77(1):136-141.e5. doi:10.1016/j.jaad.2017.02.054
AMA 11
Adil A, Godwin M. The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis. Jour. Amer. Acad. Derm.. 2017;77(1):136-141.e5. doi:10.1016/j.jaad.2017.02.054
Chicago
Adil, A., and Godwin, M.. 2017. "The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis." Journal of the American Academy of Dermatology 77 (1): 136-141.e5. https://doi.org/10.1016/j.jaad.2017.02.054
MLA 9
Adil, A., and Godwin M. "The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis." Journal of the American Academy of Dermatology, vol. 77, no. 1, 2017, pp. 136-141.e5. doi:10.1016/j.jaad.2017.02.054.
PMID
28396101 ↗
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 약물 | minoxidil
|
미녹시딜 | dict | 6 | |
| 약물 | minoxidil
|
미녹시딜 | dict | 6 | |
| 질환 | androgenetic alopecia
|
안드로겐성 탈모 | dict | 6 | |
| 질환 | androgenetic alopecia
|
안드로겐성 탈모 | dict | 6 | |
| 약물 | finasteride
|
피나스테리드 | dict | 3 | |
| 약물 | finasteride
|
피나스테리드 | dict | 3 | |
| 질환 | male pattern hair loss
|
남성형 탈모 | dict | 1 | |
| 질환 | male pattern hair loss
|
남성형 탈모 | dict | 1 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 7/8 (88%)
· 참조 0편 · 후속 7편
이 논문을 인용한 후속 연구 20
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- Minoxidil and its use in hair disorders: a review.
- Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options.
- Androgenetic alopecia: An update.
- Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Fina…
- Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature.
- A systematic summary of survival and death signalling during the life of hair follicle stem cells.
- Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs.
- Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature.
- Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and…
- The Inflammatory Aspect of Male and Female Pattern Hair Loss.
- Examining the Safety and Efficacy of Low-Level Laser Therapy for Male and Female Pattern Hair Loss: …
- Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling…
- The Biology and Genomics of Human Hair Follicles: A Focus on Androgenetic Alopecia.
- Modulation of Hair Growth Promoting Effect by Natural Products.
- Comparative effectiveness of low-level laser therapy for adult androgenic alopecia: a system review …
- The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia.
- Association between Androgenetic Alopecia and Psychosocial Disease Burden: A Cross-Sectional Survey …
- Status of research on the development and regeneration of hair follicles.
- The Efficacy and Safety of Oral and Topical Spironolactone in Androgenetic Alopecia Treatment: A Sys…
같은 제1저자의 인용 많은 논문 (3)
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- 피나스테리드가 전립선암 발생에 미치는 영향.
- COVID-19의 50가지 이상의 장기 후유증: 체계적 문헌고찰 및 메타분석.
- 양성 전립선 비대증의 임상적 진행에 대한 doxazosin, finasteride 및 병용 요법의 장기 효과.
- 양성 전립선 비대증 환자에서 finasteride의 효과. The Finasteride Study Group.
- 양성 전립선 비대증 남성에서 급성 요폐의 위험과 수술적 치료 필요성에 대한 finasteride의 효과. Finasteride Long-Term Efficacy and Safety Study Group.
- 원형 탈모.
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Epidemiology and burden of alopecia areata: a systematic review.
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