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Polo-like kinases as immune modulators: a new frontier in cancer immunotherapy.

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Trends in cancer 📖 저널 OA 21.3% 2024: 1/1 OA 2025: 2/11 OA 2026: 7/35 OA 2024~2026 2025 Vol.11(11) p. 1037-1040
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Jaiswal T, Chhabra G, Ahmad N

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Cancer immunotherapy has transformed treatment but faces challenges such as immune evasion and toxicity.

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APA Jaiswal T, Chhabra G, Ahmad N (2025). Polo-like kinases as immune modulators: a new frontier in cancer immunotherapy.. Trends in cancer, 11(11), 1037-1040. https://doi.org/10.1016/j.trecan.2025.08.003
MLA Jaiswal T, et al.. "Polo-like kinases as immune modulators: a new frontier in cancer immunotherapy.." Trends in cancer, vol. 11, no. 11, 2025, pp. 1037-1040.
PMID 40885612 ↗

Abstract

Cancer immunotherapy has transformed treatment but faces challenges such as immune evasion and toxicity. Polo-like kinases (PLKs), frequently dysregulated in tumors, are emerging as key immune modulators. Combining PLK inhibition with immunotherapy may overcome resistance, enhance antitumor responses, and improve clinical outcomes, offering an optimally efficient strategy for cancer treatment.

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