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Paradoxical control of multifocal mammary oncogenesis by radiation therapy.

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Oncoimmunology 📖 저널 OA 100% 2025: 71/71 OA 2026: 27/27 OA 2025~2026 2025 Vol.14(1) p. 2458886
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Galluzzi L, Buqué A

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In an immunocompetent mouse model of multifocal, metachronous HR mammary carcinogenesis, we have recently demonstrated that a superior control of primary neoplastic lesions by focal radiotherapy does

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APA Galluzzi L, Buqué A (2025). Paradoxical control of multifocal mammary oncogenesis by radiation therapy.. Oncoimmunology, 14(1), 2458886. https://doi.org/10.1080/2162402X.2025.2458886
MLA Galluzzi L, et al.. "Paradoxical control of multifocal mammary oncogenesis by radiation therapy.." Oncoimmunology, vol. 14, no. 1, 2025, pp. 2458886.
PMID 39873285 ↗

Abstract

In an immunocompetent mouse model of multifocal, metachronous HR mammary carcinogenesis, we have recently demonstrated that a superior control of primary neoplastic lesions by focal radiotherapy does not necessarily translate into improved oncosuppression at non-irradiated (pre)malignant tissues. These data point to a link between local tumor control by radiotherapy and systemic oncogenesis that remains to be fully understood.

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