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Atezolizumab With Bevacizumab and Nonplatinum Chemotherapy for Recurrent Ovarian Cancer: Final Results From the Placebo-Controlled AGO-OVAR 2.29/ENGOT-ov34 Phase III Trial.

무작위 임상시험 1/5 보강

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 📖 저널 OA 34.4% 2022~2026 2026 Vol.44(2) p. 103-116

PICO 자동 추출 (휴리스틱, conf 3/4)

유사 논문

P · Population 대상 환자/모집단

574 patients randomly assigned between September 2018 and July 2022, 72% were bevacizumab-pretreated, 36% had received three previous treatment lines, 26% had PD-L1-positive tumors, and 54% received paclitaxel with study therapy.

I · Intervention 중재 / 시술

three previous treatment lines, 26% had PD-L1-positive tumors, and 54% received paclitaxel with study therapy

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

[CONCLUSION] Combining atezolizumab with bevacizumab and chemotherapy did not significantly improve OS or PFS in patients with recurrent ovarian cancer ineligible for platinum. The safety profile was as expected from previous experience with these drugs.

Harter P, Marmé F, Redondo A, Reuss A, Lindemann K, Kurzeder C

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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