The yin and yang of bacterial Asn in tumor biology.
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In this issue of Cell Host & Microbe, Qiao et al.
APA
Lobel L (2026). The yin and yang of bacterial Asn in tumor biology.. Cell host & microbe, 34(1), 7-8. https://doi.org/10.1016/j.chom.2025.12.011
MLA
Lobel L. "The yin and yang of bacterial Asn in tumor biology.." Cell host & microbe, vol. 34, no. 1, 2026, pp. 7-8.
PMID
41539298 ↗
Abstract 한글 요약
In this issue of Cell Host & Microbe, Qiao et al. show that Bacteroides asparaginase reshapes anti-tumor immunity. When bacteria deplete asparagine, CD8⁺ T cells lose stemness and effector capacity, promoting tumor progression and weakening anti-PD-1 therapy. Deleting asparaginase restores asparagine to the tumor, enhancing anti-tumor immunity and immunotherapy.