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Single-cell atlas of axial skeletal immune-matrix interaction in spondylitis.

1/5 보강
Immunologic research 2026 Vol.74(1) p. 8
Retraction 확인
출처
PubMed DOI

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
환자: active disease and 12 age-matched controls undergoing spine surgery (total 108,752 single cells)
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
This integrated single-cell atlas identifies a pathogenic CTL-stromal axis in the axial skeleton of AS patients, linking immune cytotoxic mechanisms with matrix remodeling and osteogenesis. These findings delineate actionable molecular crosstalk nodes that could inform precision therapeutic strategies aimed at immune-matrix interactions in situ.Clinical trial numberNot applicable.

Wang S, Xu M, Zhang P, Hu P, Yang Y

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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