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Non-clear-cell renal cell carcinoma has an immune cold phenotype that impacts response to immune checkpoint inhibitors.

1/5 보강
Molecular cancer research : MCR 📖 저널 OA 51.1% 2023: 2/2 OA 2025: 12/16 OA 2026: 9/25 OA 2023~2026 2026
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
266 patients, 56 (21%) were histopathologically diagnosed with nccRCC.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
In conclusion, the downregulation of immune-related pathways, caused by an "immune-cold" TIME phenotype, is potentially involved in the pathogenesis underlying the decrease in the therapeutic efficacy of ICI combination therapy for nccRCC.

Ishihara H, Liu YY, Yamashita R, Fukuda H, Mizoguchi Y, Yamashita M


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