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Immune Checkpoint Signatures Reveal Stage-Specific Biomarkers for High-Activity Multiple Sclerosis.

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International journal of molecular sciences 📖 저널 OA 100% 2021~2026 2026 Vol.27(4) OA

PICO 자동 추출 (휴리스틱, conf 2/4)

P · Population 대상 환자/모집단

환자: highly active multiple sclerosis (HAMS) is crucial for guiding therapeutic decisions and initiating high-efficacy treatment strategies

I · Intervention 중재 / 시술

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C · Comparison 대조 / 비교

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O · Outcome 결과 / 결론

The immunological landscape of HAMS evolves across disease stages. In addition, we defined progression-associated markers detectable at the outset of follow-up, enabling the timely recognition of patients at heightened risk of disability accumulation, discriminating between neurodegeneration-driven and inflammation-driven mechanisms of progression.

López-Molina M, Torres Iglesias G, Vidal L, Díaz Gamero N, Sánchez-Pascual Á, Chamorro B

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