Regulatory T cells thrive in ammonia-rich tumors.
1/5 보강
In a recent issue of Cell, Gu et al.
APA
Ye C, Delgoffe GM (2026). Regulatory T cells thrive in ammonia-rich tumors.. Cell metabolism, 38(3), 447-448. https://doi.org/10.1016/j.cmet.2026.02.003
MLA
Ye C, et al.. "Regulatory T cells thrive in ammonia-rich tumors.." Cell metabolism, vol. 38, no. 3, 2026, pp. 447-448.
PMID
41780498 ↗
Abstract 한글 요약
In a recent issue of Cell, Gu et al. find that regulatory T (Treg) cells metabolize tumor-derived ammonia via the urea cycle and spermine synthesis, promoting immunosuppression through PPARγ-dependent oxidative phosphorylation. Inhibition of tumor glutamine metabolism reduces ammonia levels and overcomes Treg cell-mediated resistance to anti-PD-1 therapy.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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