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Expression of PD-1/PD-L1 pathway molecules in human cardiac allograft according to acute cellular rejection status: insights from a Korean Heart Transplant Cohort.

1/5 보강

Journal of pathology and translational medicine 📖 저널 OA 68% 2021~2026 2026 OA

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

78 patients with heart TPL were subjected to immunohistochemistry for PD-L1, PD-1, CD4, and CD8.

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

[CONCLUSIONS] The PD-1/PD-L1 pathway is involved in ACR regulation in human cardiac allografts. Increased PD-L1 expression during ACR may represent a counteractive mechanism to limit alloimmune-mediated tissue injury, supporting PD-1/PD-L1 as a potential therapeutic target in heart TPL recipients.

Yim J, Jeon YK, Chung DH, Koh J

📖 무료 전문 🔓 OA PDF unpaywall · cc-by-nc

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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